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所选碳水化合物的作用以及酚氧化酶原级联系统对铜绿假单胞菌和奇异变形杆菌菌株黏附于未免疫的大蜡螟幼虫血细胞的贡献。

Effects of selected carbohydrates and the contribution of the prophenoloxidase cascade system to the adhesion of strains of Pseudomonas aeruginosa and Proteus mirabilis to hemocytes of nonimmune larval Galleria mellonella.

作者信息

Dunphy G B, Chadwick J S

机构信息

Department of Microbiology and Immunology, Queen's University, Kingston, Ont., Canada.

出版信息

Can J Microbiol. 1989 Apr;35(4):524-7. doi: 10.1139/m89-083.

DOI:10.1139/m89-083
PMID:2501016
Abstract

The adhesion of strains of Pseudomonas aeruginosa and Proteus mirabilis to the plasmatocytes and granular cells of nonimmune larval Galleria mellonella was influenced by and varied with the type of carbohydrate. Laminarin enhanced prophenoloxidase activation and bacterial adhesion to the hemocytes whereas sucrose suppressed both activities. For all other sugars there was no correlation between bacterial adhesion to the hemocytes and phenoloxidase activity. It is proposed that bacterial adhesion to the hemocytes may be mediated by both lectinlike binding and components of the prophenoloxidase activating system acting like opsonins.

摘要

铜绿假单胞菌和奇异变形杆菌菌株对未免疫的大蜡螟幼虫血浆细胞和颗粒细胞的黏附受到碳水化合物类型的影响且随其变化。海带多糖增强了酚氧化酶原激活和细菌对血细胞的黏附,而蔗糖则抑制了这两种活性。对于所有其他糖类,细菌对血细胞的黏附与酚氧化酶活性之间没有相关性。有人提出,细菌对血细胞的黏附可能由类凝集素结合和像调理素一样起作用的酚氧化酶原激活系统的成分介导。

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