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免疫和非免疫的大蜡螟幼虫血细胞对奇异变形杆菌的反应。

Reactions of hemocytes of immune and non-immune Galleria mellonella larvae to Proteus mirabilis.

作者信息

Morton D B, Dunphy G B, Chadwick J S

出版信息

Dev Comp Immunol. 1987 Winter;11(1):47-55. doi: 10.1016/0145-305x(87)90007-3.

DOI:10.1016/0145-305x(87)90007-3
PMID:3109970
Abstract

Immune larval Galleria mellonella removed live Proteus mirabilis from the hemolymph less effectively than did non-immune larvae. This was attributed to a decline in total hemocyte counts, levels of plasmatocytes and granulocytes and hemocyte adhesion capacity. Immune serum possessed factors which reduced bacterial adhesion to the hemocytes. This was not due to altering bacterial surfaces but rather to irreversible suppression of hemocyte activity.

摘要

免疫的大蜡螟幼虫从血淋巴中清除奇异变形杆菌活菌体的效率低于非免疫幼虫。这归因于血细胞总数、浆细胞和粒细胞水平以及血细胞黏附能力的下降。免疫血清含有降低细菌对血细胞黏附的因子。这不是由于改变细菌表面,而是由于对血细胞活性的不可逆抑制。

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