Mayo Clinic, Rochester, MN; International Clinical Research Center, St Anne's Hospital, Brno, Czech Republic.
Mayo Clinic, Rochester, MN.
Chest. 2014 Jul;146(1):228-234. doi: 10.1378/chest.14-0084.
Sleep-disordered breathing (SDB) may be a treatable risk factor in patients with hypertrophic cardiomyopathy (HCM), the most common inherited cardiomyopathy. Evidence suggests a high prevalence of SDB in HCM. We summarize the pathophysiology of SDB as it relates to hypertension, coronary artery disease, atrial fibrillation, and sudden cardiac death in patients with HCM. The implications regarding the care of patients with HCM and SDB are discussed as well as the knowledge deficits needing further exploration.
睡眠呼吸紊乱(SDB)可能是肥厚型心肌病(HCM)患者的一种可治疗的危险因素,HCM 是最常见的遗传性心肌病。有证据表明,HCM 患者中 SDB 的患病率很高。我们总结了 SDB 与 HCM 患者的高血压、冠状动脉疾病、心房颤动和心源性猝死之间的病理生理学关系。还讨论了与 HCM 和 SDB 患者护理相关的意义以及需要进一步探索的知识缺陷。