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[卢森堡大公国结直肠癌的发病率及患者生存率]

[Incidence of colorectal carcinoma and patient survival in the Grand-Duchy of Luxembourg].

作者信息

Hammer G P, Pescatore P, Braun M, Wagener Y, Scheiden R

出版信息

Bull Soc Sci Med Grand Duche Luxemb. 2014(1):27-44.

Abstract

As in many other Western countries, colorectal cancer is one of the most common malignant tumours in Luxembourg. It is thus an important target for prevention measures. In light of the discussions on the introduction of organized screening programmes in Luxembourg a description of the current cancer incidence and relative survival rates, as well as a comparison with neighbouring countries are important. The tumour incidence is comparable to that in other countries with similar socio-economic development. The standardized incidence rate (world population) in 2010 was 26.4 and 44.4 per 100,000 for women and men, respectively. In some, but not all, Western European countries, a decreasing trend of the standardized incidence is emerging. No such trend is currently observed in Luxembourg. The mortality and relative survival rates are comparable to those in other European countries. The proportion of colorectal carcinomas of stages T1 + T2, 18.7% in the years 2000 to 2011, is markedly lower in Luxembourg than for example in Rhineland -Palatinate (29.4%), while the proportion of carcinomas of stage T4 is higher (17.4% versus 13.9%). This suggests that further successes in prevention are possible and illustrates the benefits of an organized screening colonoscopy program compared with opportunistic screening.

摘要

与许多其他西方国家一样,结直肠癌是卢森堡最常见的恶性肿瘤之一。因此,它是预防措施的重要目标。鉴于卢森堡关于引入有组织筛查计划的讨论,描述当前的癌症发病率和相对生存率,以及与邻国进行比较很重要。该国的肿瘤发病率与社会经济发展水平相似的其他国家相当。2010年的标准化发病率(世界人口),女性和男性分别为每10万人26.4例和44.4例。在一些(但不是所有)西欧国家,标准化发病率呈下降趋势。目前在卢森堡未观察到这种趋势。死亡率和相对生存率与其他欧洲国家相当。2000年至2011年期间,T1 + T2期结直肠癌的比例为18.7%,卢森堡这一比例明显低于例如莱茵兰 - 普法尔茨州(29.4%),而T4期癌的比例更高(分别为17.4%和13.9%)。这表明预防方面有可能取得进一步成功,并说明了有组织的筛查结肠镜检查计划相对于机会性筛查的益处。

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