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膝关节损伤的生物治疗进展:全层软骨缺损

Updates in biological therapies for knee injuries: full thickness cartilage defect.

机构信息

Division of Orthopaedic Surgery, Hospital Israelita Albert Einstein, Avenida Albert Einstein, 627/701 - 3 Andar/Bloco A1, Morumbi, 05651-901, São Paulo, SP, Brazil.

出版信息

Curr Rev Musculoskelet Med. 2014 Sep;7(3):256-62. doi: 10.1007/s12178-014-9226-y.

Abstract

Full thickness cartilage defect might occur at different ages, but a focal defect is a major concern in the knee of young athletes. It causes impairment and does not heal by itself. Several techniques were described to treat symptomatic full thickness cartilage defect. Recently, several advances were described on the known techniques of microfracture, osteochondral allograft, cell therapy, and others. This article brings an update of current literature on these well-described techniques for full thickness cartilage defect.

摘要

全层软骨缺损可能发生在不同的年龄,但在年轻运动员的膝关节中,局灶性缺损是一个主要关注点。它会导致功能障碍,而且不会自行愈合。已经描述了几种技术来治疗有症状的全层软骨缺损。最近,对已知的微骨折、骨软骨同种异体移植、细胞治疗等技术进行了一些改进。本文对全层软骨缺损这些描述良好的技术的现有文献进行了更新。

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本文引用的文献

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UPDATING ON DIAGNOSIS AND TREATMENT OF CHONDRAL LESION OF THE KNEE.膝关节软骨损伤的诊断与治疗进展
Rev Bras Ortop. 2015 Nov 16;47(1):12-20. doi: 10.1016/S2255-4971(15)30339-6. eCollection 2012 Jan-Feb.
9
Cartilage extra-cellular matrix biomembrane for the enhancement of microfractured defects.用于增强微骨折缺陷的软骨细胞外基质生物膜。
Knee Surg Sports Traumatol Arthrosc. 2014 Jun;22(6):1249-59. doi: 10.1007/s00167-013-2716-4. Epub 2013 Nov 21.

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