Department of Internal Medicine and Medical Disciplines'Sapienza' University of Rome, Viale del Policlinico 155, 00161 Rome, ItalyUnit of Internal Medicine'Casa Sollievo della Sofferenza' Hospital, IRCCS, Viale dei Cappuccini snc, 71013 San Giovanni Rotondo, Foggia, ItalyFaculty of Economics (L.N.)LUSPIO University, Via delle Sette Chiese 139, 00145 Rome, ItalyMetabolic Bone Diseases UnitDivision of Endocrinology, Department of Medicine, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, New York 10032, USA
Department of Internal Medicine and Medical Disciplines'Sapienza' University of Rome, Viale del Policlinico 155, 00161 Rome, ItalyUnit of Internal Medicine'Casa Sollievo della Sofferenza' Hospital, IRCCS, Viale dei Cappuccini snc, 71013 San Giovanni Rotondo, Foggia, ItalyFaculty of Economics (L.N.)LUSPIO University, Via delle Sette Chiese 139, 00145 Rome, ItalyMetabolic Bone Diseases UnitDivision of Endocrinology, Department of Medicine, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, New York 10032, USA.
Eur J Endocrinol. 2014 Oct;171(4):481-7. doi: 10.1530/EJE-14-0493. Epub 2014 Jul 11.
Primary hyperparathyroidism (PHPT) is one of the most frequently diagnosed endocrine disorders, but few studies have focused on hospital management of the disease in Europe. We investigated the frequency of hospital admission for diagnosis and surgical treatment of PHPT in Italy.
A retrospective study was conducted for investigating the hospital care for PHPT in Italy.
We retrieved data from the 'Record of Hospital Discharge' of the Italian Health Ministry, from 2006 to 2011, and analyzed the codes corresponding to PHPT-related diagnoses and surgical procedures.
Overall, 46 275 hospitalization episodes for PHPT were identified during the entire period (69% in women and 31% in men; mean age 63.3±39.8 years). Patients' mean age significantly increased during the years (P<0.001). The mean length of stay was 8.2±10.5 days (28% of the episodes requiring <3 days of stay). Admissions for surgical procedures were 12 457 accounting for 26.9% of the total hospitalizations. There was a trend to a significant increase in the percentage of surgery (P<0.05). The mean hospitalization rate for PHPT was 12.9/100 000 inhabitants per year and the trend showed a significant decrease during the period of 2006-2011 (P<0.0001). The mean hospitalization rate for PHPT surgery was 3.65/100 000 per year, which significantly increased over time (P<0.001).
PHPT considerably influences the Italian Hospital healthcare system. We observed a tendency to a decrease in the frequency of hospitalization during the period of 2006-2011, most probably because of economic issues, a concomitant increased age of patients, and, interestingly, also a progressive increase in the percentage of surgical treatment among patients admitted for PHPT.
原发性甲状旁腺功能亢进症（PHPT）是最常见的内分泌疾病之一，但在欧洲，很少有研究关注该病的医院管理。我们研究了意大利 PHPT 患者的住院诊断和手术治疗频率。
回顾性研究调查了意大利 PHPT 的医院治疗情况。
我们从 2006 年至 2011 年从意大利卫生部的“住院记录”中检索数据，并分析了与 PHPT 相关的诊断和手术程序的代码。
在整个研究期间，共发现 46275 例 PHPT 住院病例（69%为女性，31%为男性；平均年龄 63.3±39.8 岁）。患者的平均年龄在研究期间显著增加（P<0.001）。平均住院时间为 8.2±10.5 天（28%的住院时间<3 天）。接受手术的住院人数为 12457 人，占总住院人数的 26.9%。手术比例呈上升趋势（P<0.05）。PHPT 的年住院率为 12.9/100000 居民，2006-2011 年期间呈显著下降趋势（P<0.0001）。PHPT 手术的年住院率为 3.65/100000，呈逐年显著上升趋势（P<0.001）。
PHPT 对意大利医院医疗系统有很大影响。我们观察到 2006-2011 年期间住院频率呈下降趋势，这很可能是由于经济问题、患者年龄的增长，以及有趣的是，PHPT 患者接受手术治疗的比例也呈上升趋势。
