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针对来自4兆伏至25兆伏的10厘米×10厘米和3厘米×3厘米光子束中圆柱形电离室的kQ因子进行实验测定。

Experimental determination of kQ factors for cylindrical ionization chambers in 10 cm × 10 cm and 3 cm × 3 cm photon beams from 4 MV to 25 MV.

作者信息

Krauss A, Kapsch R P

机构信息

Physikalisch-Technische Bundesanstalt, Bundesallee 100, D-38116 Braunschweig, Germany.

出版信息

Phys Med Biol. 2014 Aug 7;59(15):4227-46. doi: 10.1088/0031-9155/59/15/4227. Epub 2014 Jul 14.

Abstract

For the ionometric determination of absorbed dose to water, Dw, in megavoltage photon beams from a linear accelerator, beam-quality-dependent correction factors, kQ, are used for the ionization chambers. By using a water calorimeter, these factors can be determined experimentally and with substantially lower standard uncertainties compared to calculated values of the kQ, which are published in various dosimetry protocols. In this investigation, kQ for different types of cylindrical ionization chambers (NE 2561, NE 2571, FC 65 G) were determined experimentally in 10 cm × 10 cm photon beams from 4 MV to 25 MV (corresponding beam quality index TPR20,10 from 0.64 to 0.80). The measurements were carried out at the linear accelerator facility of the Physikalisch-Technische Bundesanstalt. It is shown that the kQ factors for a single ionization chamber in 10 cm × 10 cm photon beams can be measured with a relative standard uncertainty of 0.31%. In addition to these measurements in 10 cm × 10 cm fields, kQ factors for the NE 2561 chamber were also determined in smaller 3 cm × 3 cm photon beams between 6 MV and 25 MV. In this case, relative standard uncertainties between 0.35 % and 0.38 % are achieved for the kQ factors. It is found for this ionization chamber, that the ratio of the kQ factors in 3 cm × 3 cm and in 10 cm × 10 cm beams increases with increasing TPR20,10 to reach a value of 1.0095 at TPR20,10 = 0.8 with a relative standard uncertainty of 0.4 %.

摘要

对于利用离子测量法测定直线加速器兆伏级光子束中水的吸收剂量(D_w),电离室需使用与射束质相关的校正因子(k_Q)。通过使用水热计,与各种剂量测定规程中公布的(k_Q)计算值相比,这些因子能够通过实验测定,且标准不确定度要低得多。在本研究中,在4兆伏至25兆伏的10厘米×10厘米光子束中(相应的射束质指数(TPR_{20,10})从0.64至0.80),对不同类型的圆柱形电离室(NE 2561、NE 2571、FC 65 G)的(k_Q)进行了实验测定。测量在德国联邦物理技术研究院的直线加速器设施上进行。结果表明,在10厘米×10厘米光子束中,单个电离室的(k_Q)因子能够以0.31%的相对标准不确定度进行测量。除了在10厘米×10厘米射野中的这些测量外,还在6兆伏至25兆伏的较小3厘米×3厘米光子束中测定了NE 2561室的(k_Q)因子。在这种情况下,(k_Q)因子的相对标准不确定度在0.35%至0.38%之间。对于该电离室发现,3厘米×3厘米和10厘米×10厘米射束中(k_Q)因子的比值随着(TPR_{20,10})的增加而增大,在(TPR_{20,10}=0.8)时达到1.0095的值,相对标准不确定度为0.4%。

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