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直接测定 6 MeV 至 20 MeV 高能电子束中圆柱形和平行板电离室的 k 因子。

Direct determination of k factors for cylindrical and plane-parallel ionization chambers in high-energy electron beams from 6 MeV to 20 MeV.

机构信息

Author to whom any correspondence should be addressed.

出版信息

Phys Med Biol. 2018 Feb 6;63(3):035041. doi: 10.1088/1361-6560/aaa71e.

Abstract

For the ionometric determination of the absorbed dose to water, D , in high-energy electron beams from a clinical accelerator, beam quality dependent correction factors, k , are required. By using a water calorimeter, these factors can be determined experimentally and potentially with lower standard uncertainties than those of the calculated k factors, which are tabulated in various dosimetry protocols. However, one of the challenges of water calorimetry in electron beams is the small measurement depths in water, together with the steep dose gradients present especially at lower energies. In this investigation, water calorimetry was implemented in electron beams to determine k factors for different types of cylindrical and plane-parallel ionization chambers (NE2561, NE2571, FC65-G, TM34001) in 10 cm  ×  10 cm electron beams from 6 MeV to 20 MeV (corresponding beam quality index R ranging from 1.9 cm to 7.5 cm). The measurements were carried out using the linear accelerator facility of the Physikalisch-Technische Bundesanstalt. Relative standard uncertainties for the k factors between 0.50% for the 20 MeV beam and 0.75% for the 6 MeV beam were achieved. For electron energies above 8 MeV, general agreement was found between the relative electron energy dependencies of the k factors measured and those derived from the AAPM TG-51 protocol and recent Monte Carlo-based studies, as well as those from other experimental investigations. However, towards lower energies, discrepancies of up to 2.0% occurred for the k factors of the TM34001 and the NE2571 chamber.

摘要

对于临床加速器中高能电子束的水吸收剂量 D 的离子计测定,需要使用束质依赖性修正因子 k。通过使用水热计,可以实验确定这些因子,并且潜在地可以比在各种剂量学协议中列出的计算 k 因子具有更低的标准不确定度。然而,电子束中水热计的挑战之一是水的小测量深度,以及尤其是在较低能量下存在的陡峭剂量梯度。在这项研究中,水热计在电子束中得到了实施,以确定不同类型的圆柱形和平行板电离室(NE2561、NE2571、FC65-G、TM34001)的 k 因子,能量范围从 6 MeV 到 20 MeV(相应的束质指数 R 从 1.9 cm 到 7.5 cm)。测量是在 Physikalisch-Technische Bundesanstalt 的线性加速器设施中进行的。对于 20 MeV 束,k 因子的相对标准不确定度为 0.50%,对于 6 MeV 束,k 因子的相对标准不确定度为 0.75%。对于高于 8 MeV 的电子能量,发现测量的 k 因子的相对电子能量依赖性与 AAPM TG-51 协议和最近基于蒙特卡罗的研究以及其他实验研究得出的依赖性之间存在普遍一致性。然而,对于较低的能量,TM34001 和 NE2571 室的 k 因子的差异高达 2.0%。

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