Carr M E, Howe C W
Coagulation Special Studies Laboratory, Medical College of Virginia, Richmond.
South Med J. 1989 Jul;82(7):921-3. doi: 10.1097/00007611-198907000-00032.
This report describes the case of a young woman with biopsy-proven neurofibromatosis and a history of recurrent fetal wastage who had sudden onset of slurred speech and left-sided weakness. CT scan and MRI revealed multiple cerebral infarcts. Laboratory evaluation revealed lupus anticoagulant and high levels of anticardiolipin antibody. This case illustrates the thrombotic tendencies seen in patients with lupus anticoagulant and anticardiolipin antibody, and is the first reported case of LA in association with neurofibromatosis.
本报告描述了一名年轻女性的病例，该女性经活检证实患有神经纤维瘤病，并有反复胎儿流产史，突然出现言语不清和左侧肢体无力。CT扫描和MRI显示多发性脑梗死。实验室检查发现狼疮抗凝物和高水平的抗心磷脂抗体。该病例说明了狼疮抗凝物和抗心磷脂抗体患者中存在的血栓形成倾向，并且是首例报告的狼疮抗凝物与神经纤维瘤病相关的病例。
