Cueto-Manzano Alfonso M, Martínez-Ramírez Héctor R, Cortés-Sanabria Laura
Unidad de Investigación Médica en Enfermedades Renales, Hospital de Especialidades , Jalisco, Mexico.
Kidney Int Suppl (2011). 2013 May;3(2):210-214. doi: 10.1038/kisup.2013.16.
Negative lifestyle habits (potential risks for chronic kidney disease, CKD) are rarely modified by physicians in a conventional health-care model (CHCM). Multidisciplinary strategies may have better results; however, there is no information on their application in the early stages of CKD. Thus, the aim of this study was to compare a multiple intervention model versus CHCM on lifestyle and renal function in patients with type 2 diabetes mellitus and CKD stage 1-2. In a prospective cohort study, a family medicine unit (FMU) was assigned a multiple intervention model (MIM) and another continued with conventional health-care model (CHCM). MIM patients received an educational intervention guided by a multidisciplinary team (family physician (FP), social worker, dietitian, physical trainer); self-help groups functioned with free activities throughout the study. CHCM patients were managed only by the FP, who decided if patients needed referral to other professionals. Thirty-nine patients were studied in each cohort. According to a lifestyle questionnaire, no baseline differences were found between cohorts, but results reflected an unhealthy lifestyle. After 6 months of follow-up, both cohorts showed significant improvement in their dietary habits. Compared to CHCM diet, exercise, emotional management, knowledge of disease, and adherence to treatment showed greater improvement in the MIM. Blood pressure decreased in both cohorts, but body mass index, waist circumference, and HbA significantly decreased only in MIM. Glomerular filtration rate (GFR) was maintained equally in both cohorts, but albuminuria significantly decreased only in MIM. In conclusion, MIM achieves better control of lifestyle-related variables and CKD risk factors in type 2 diabetes mellitus (DM2) patients with CKD stage 1-2. Broadly, implementation of a MIM in primary health care may produce superior results that might assist in preventing the progression of CKD.
在传统医疗模式(CHCM)中,医生很少能改变负面的生活方式习惯(慢性肾脏病,CKD的潜在风险)。多学科策略可能会取得更好的效果;然而,尚无关于其在CKD早期阶段应用的信息。因此,本研究的目的是比较多干预模式与CHCM对2型糖尿病和CKD 1-2期患者生活方式和肾功能的影响。在一项前瞻性队列研究中,一个家庭医学单元(FMU)被分配采用多干预模式(MIM),另一个则继续采用传统医疗模式(CHCM)。MIM组患者接受由多学科团队(家庭医生(FP)、社会工作者、营养师、体能教练)指导的教育干预;在整个研究过程中,自助小组开展免费活动。CHCM组患者仅由FP管理,FP决定患者是否需要转诊至其他专业人员。每个队列研究了39名患者。根据生活方式问卷,两组之间未发现基线差异,但结果反映出不健康的生活方式。经过6个月的随访,两组的饮食习惯均有显著改善。与CHCM组相比,MIM组在饮食、运动、情绪管理、疾病知识和治疗依从性方面有更大改善。两组的血压均下降,但仅MIM组的体重指数、腰围和糖化血红蛋白显著下降。两组的肾小球滤过率(GFR)保持相同,但仅MIM组的蛋白尿显著下降。总之,MIM能更好地控制1-2期CKD的2型糖尿病(DM2)患者与生活方式相关的变量和CKD危险因素。广泛而言,在初级卫生保健中实施MIM可能会产生更好的效果,有助于预防CKD的进展。