Watne K, Tverå K, Hager B, Nornes H, Hirschberg H
Tidsskr Nor Laegeforen. 1989 Jun 30;109(19-21):2017-8.
The article describes a method making it possible to give high radiation doses to a localized volume of the brain while sparing normal surrounding brain tissue. The treatment consists of sending multiple narrow radiation beams from different directions to the volume of tissue to be treated by rotating the radiation source and the patient table in relation to each other. Mega-voltage radiation from a linear accelerator is used. A non-invasive stereotactic frame is mounted on the patient and a CT scan of the brain is performed to localize the center and extent of the tissue to be treated. The radiation treatment is then given by using the coordinates on the frame to assure that the center of rotation of the treatment table and the linear accelerator pass through the center of the volume of tissue. The method has been used to give radiation boosts after external radiation to brain tumours, and to treat patients with recurrent tumours. Small localized benign intracranial tumours and AV-malformations have also been treated.
本文描述了一种方法，该方法能够在保护周围正常脑组织的同时，对脑内局部区域给予高剂量辐射。治疗方法是通过使辐射源和患者治疗床相对旋转，从不同方向向待治疗的组织区域发射多条窄辐射束。使用直线加速器产生的兆伏级辐射。在患者身上安装一个非侵入性立体定向框架，并对脑部进行CT扫描，以确定待治疗组织的中心和范围。然后通过使用框架上的坐标进行放射治疗，以确保治疗床和直线加速器的旋转中心穿过组织区域的中心。该方法已用于脑肿瘤外照射后的剂量增强治疗，以及复发性肿瘤患者的治疗。小型局限性颅内良性肿瘤和动静脉畸形也已得到治疗。
