Choi Jong-Hoo, Heim Leo E, Ahrens Mike, Prechtl Martin H G
Department of Chemistry, University of Cologne, Greinstr. 6, 50939 Cologne, Germany.
Dalton Trans. 2014 Dec 14;43(46):17248-54. doi: 10.1039/c4dt01634c.
In this work, we present a mild method for direct conversion of primary alcohols into carboxylic acids with the use of water as an oxygen source. Applying a ruthenium dihydrogen based dehydrogenation catalyst for this cause, we investigated the effect of water on the catalytic dehydrogenation process of alcohols. Using 1 mol% of the catalyst we report up to high yields. Moreover, we isolated key intermediates which most likely play a role in the catalytic cycle. One of the intermediates was identified as a trans dihydrido carbonyl complex which is generated in situ in the catalytic process.
在本工作中，我们提出了一种温和的方法，以水作为氧源将伯醇直接转化为羧酸。为此应用基于钌二氢化物的脱氢催化剂，我们研究了水对醇催化脱氢过程的影响。使用1 mol%的催化剂，我们报道了高达高产率的结果。此外，我们分离出了可能在催化循环中起作用的关键中间体。其中一种中间体被鉴定为在催化过程中原位生成的反式二氢羰基配合物。
