Loker Hydrocarbon Research Institute and Department of Chemistry, University of Southern California, 837 Bloom Walk, Los Angeles, CA 90089-1661, USA.
Chem Commun (Camb). 2018 Jul 10;54(56):7711-7724. doi: 10.1039/c8cc03412e.
Selective hydrogen transfer remains a central research focus in catalysis: hydrogenation and dehydrogenation have central roles, both historical and contemporary, in all aspects of fuel, agricultural, pharmaceutical, and fine chemical synthesis. Our lab has been involved in this area by designing homogeneous catalysts for dehydrogenation and hydrogen transfer that fill needs ranging from on-demand hydrogen storage to fine chemical synthesis. A keen eye toward mechanism has enabled us to develop systems with excellent selectivity and longevity and demonstrate these in a diversity of high-value applications. Here we describe recent work from our lab in these areas that are linked by a central mechanistic trichotomy of catalyst initiation pathways that lead highly analogous precursors to a diversity of useful applications.
加氢和脱氢在燃料、农业、制药和精细化学品合成的各个方面都具有历史和当代的核心作用。我们的实验室通过设计用于脱氢和氢转移的均相催化剂参与了这一领域，这些催化剂满足了从按需储氢到精细化学品合成等各种需求。对反应机制的敏锐观察使我们能够开发出具有优异选择性和长寿命的系统，并在各种高价值应用中展示这些系统。在这里，我们描述了我们实验室在这些领域的最新工作，这些工作通过催化剂引发途径的中心机制三分法联系在一起，这些途径导致高度类似的前体转化为多种有用的应用。
