J Refract Surg. 2014 Sep;30(9):598-603. doi: 10.3928/1081597X-20140709-01. Epub 2014 Jul 16.
To investigate changes to corneal surface aberrations and vision between PresbyLASIK and LASIK for correction of presbyopia using the MEL 80 platform (Carl Zeiss Meditec, Jena, Germany).
The retrospective data of 31 patients who underwent PresbyLASIK (the PresbyLASIK group) between January 2009 and November 2011 and 20 matched patients who underwent LASIK (the LASIK group) were analyzed for changes to refraction, corrected distance visual acuity, and corneal surface wavefront aberrations calculated over 4- and 6-mm pupils. Outcomes at the 3-month follow-up visit were compared to data collected immediately prior to surgery and between PresbyLASIK and LASIK correction. Associations between induced corneal aberrations and best spherical equivalent refraction were explored.
PresbyLASIK and LASIK significantly reduced refractive error in both myopes and hyperopes. Residual refractive error was not significantly different between treatment groups, except for spherical equivalent refraction, which was significantly more myopic following LASIK treatment compared to PresbyLASIK in myopes. There was no significant difference in postoperative corrected distance visual acuity between groups. LASIK and PresbyLASIK induced positive spherical aberration in myopes and negative spherical aberration in hyperopes, with significant differences between treatments only apparent in myopes when analyzed over a 4-mm pupil (PresbyLASIK group: 0.07 ± 0.06 µm; LASIK group: 0.03 ± 0.04 µm, P < .05). In hyperopes, induced spherical aberration was more highly associated with refractive change after LASIK (r = 0.82, P < .05) than PresbyLASIK (r = 0.64, P < .001); instead PresbyLASIK led to a more consistent shift of approximately 0.3 µm independent of induced change to refraction.
PresbyLASIK using the MEL 80 platform induced significant changes in spherical aberration in myopes and hyperopes. PresbyLASIK appears to offer an improved response over LASIK when correcting myopes due to an apparent increase in depth of focus resulting from changes in spherical aberration. For hyperopes, PresbyLASIK provides a more consistent spherical aberration effect independent of refractive change.
使用 MEL 80 平台（德国卡尔蔡司医疗技术公司），调查老视 LASIK（PresbyLASIK）和 LASIK 治疗老视的角膜表面像差和视力变化。
回顾性分析 2009 年 1 月至 2011 年 11 月期间 31 例接受 PresbyLASIK（PresbyLASIK 组）和 20 例匹配的接受 LASIK（LASIK 组）患者的资料，分析 4 和 6mm 瞳孔下的屈光度、矫正远视力和角膜表面波前像差的变化。比较术后 3 个月随访时的数据与术前数据以及 PresbyLASIK 和 LASIK 矫正组之间的数据。探讨诱导的角膜像差与最佳球镜等效屈光度之间的关系。
PresbyLASIK 和 LASIK 均显著降低了近视和远视患者的屈光不正。除了等效球镜屈光度，两组之间的残余屈光不正差异无统计学意义，而 LASIK 组在近视患者中的等效球镜屈光度比 PresbyLASIK 组更近视。两组间术后矫正远视力差异无统计学意义。LASIK 和 PresbyLASIK 在近视眼中诱导正球差，在远视眼中诱导负球差，仅在 4mm 瞳孔下分析时，两种治疗方法之间的差异具有统计学意义（PresbyLASIK 组：0.07±0.06μm；LASIK 组：0.03±0.04μm，P<0.05）。在远视眼中，诱导的球差与 LASIK 后（r=0.82，P<0.05）的屈光变化更相关，而与 PresbyLASIK （r=0.64，P<0.001）的相关性较低；相反，PresbyLASIK 导致的球差变化约为 0.3μm，与诱导的屈光度变化无关。
使用 MEL 80 平台的 PresbyLASIK 导致近视和远视患者的球差显著变化。与 LASIK 相比，由于球差变化导致的景深增加，PresbyLASIK 似乎为近视患者提供了更好的反应。对于远视患者，PresbyLASIK 提供了一种更一致的球差效应，与屈光变化无关。
