Ichikawa Y, Sato C, McCreary J, Lubenko A
Blood Transfusion Center, Saitama Medical School Hospital, Japan.
Vox Sang. 1989;56(2):98-100. doi: 10.1111/j.1423-0410.1989.tb04958.x.
Hemolytic disease of the newborn in a Japanese infant led to studies which indicate that an antibody detected in the maternal serum is recognizing a hitherto unknown red cell antigen. The antigen, which we have named Kg, was found in two generations of the family and it is inherited as a Mendelian dominant character. The maternal serum failed to react with the red cells of more than 600 random Japanese blood donors, 64 red cell samples known to possess low-frequency antigens and all but one of 75 red cell samples known to lack high-frequency antigens without recognized low-frequency antigens. The father's red cells were tested extensively for established low-frequency antigens; only Dia was demonstrated and the maternal antibody was shown not to contain anti-Dia.
一名日本婴儿患新生儿溶血病，由此引发的研究表明，在母体血清中检测到的一种抗体识别出一种迄今未知的红细胞抗原。我们将该抗原命名为Kg，在这个家族的两代人中都发现了它，并且它作为孟德尔显性性状遗传。母体血清与600多名随机选取的日本献血者的红细胞、已知具有低频抗原的64份红细胞样本以及已知缺乏高频抗原且无公认低频抗原的75份红细胞样本中的74份均无反应。对父亲的红细胞进行了广泛的已知低频抗原检测；仅检测到Dia，且母体抗体不含抗Dia。
