Xu-Welliver Meng, Yuh William T C, Fielding Julia R, Macura Katarzyna J, Huang Zhibin, Ayan Ahmet S, Backes Floor J, Jia Guang, Moshiri Mariam, Zhang Jun, Mayr Nina A
From the Departments of Radiation Oncology (M.X., A.S.A.), Radiology (G.J., J.Z.), and Obstetrics and Gynecology (F.J.B.), Ohio State University, Columbus, Ohio; Department of Radiology, University of North Carolina, Chapel Hill, NC (J.R.F.); Department of Radiology, Johns Hopkins University, Baltimore, Md (K.J.M.); Department of Radiation Oncology, East Carolina University, Greenville, NC (Z.H.); and Departments of Radiology (W.T.C.Y., M.M.) and Radiation Oncology (N.A.M.), University of Washington Medical Center, 1959 NE Pacific St, Seattle, WA 98195-6043.
Radiographics. 2014 Jul-Aug;34(4):1062-81. doi: 10.1148/rg.344130099.
The focus of this article is radiation therapy for gynecologic cancers, with emphasis on imaging-based treatment planning and delivery. For the various gynecologic cancers, radiation oncologists rely on essential clinical information to triage treatment options, and various imaging studies are performed for treatment planning and radiation therapy delivery. A practical approach is provided to help radiologists tailor their reports for the needs of their radiation oncology and gynecologic oncology colleagues, to optimize multidisciplinary care for patients with gynecologic cancer. Template radiology reports are proposed to address the specific information needs of oncologists at each phase-before, during, and after treatment. Fueled by the rapid progress in engineering and computer sciences during the past 2 decades, remarkable advances have been made in anatomic, functional, and molecular imaging and in radiation treatment planning and delivery in patients with gynecologic cancer. Radiation therapy has evolved from a nontargeted approach to a precisely targeted, highly conformal treatment modality, to further improve treatment outcomes and reduce morbidity. High-quality imaging has become essential for staging of the disease, delineation of tumor extent for treatment planning and delivery, and monitoring therapy response. Anatomic and functional imaging has also been shown to provide prognostic information that allows clinicians to tailor therapy on the basis of personalized patient information. This field is an area of active research, and future clinical trials are warranted to validate preliminary results in the field.
本文重点关注妇科癌症的放射治疗，着重于基于成像的治疗计划与实施。对于各种妇科癌症，放射肿瘤学家依靠基本临床信息来筛选治疗方案，并进行各种成像研究以制定治疗计划和实施放射治疗。本文提供了一种实用方法，以帮助放射科医生根据放射肿瘤学和妇科肿瘤学同事的需求来调整报告内容，从而优化对妇科癌症患者的多学科护理。本文提出了放射学报告模板，以满足肿瘤学家在治疗前、治疗期间和治疗后各阶段的特定信息需求。在过去20年中，工程学和计算机科学的迅速发展推动了妇科癌症患者在解剖学、功能和分子成像以及放射治疗计划与实施方面取得了显著进展。放射治疗已从一种非靶向方法演变为一种精确靶向、高度适形的治疗方式，以进一步改善治疗效果并降低发病率。高质量成像对于疾病分期、确定治疗计划和实施的肿瘤范围以及监测治疗反应至关重要。解剖学和功能成像也已被证明可提供预后信息，使临床医生能够根据个性化的患者信息调整治疗方案。该领域是一个活跃的研究领域，未来有必要进行临床试验以验证该领域的初步结果。
