Singh S P, Jha K
Rajendra Agricultural University, Bihar, Pusa (Samastipur), India.
Zentralbl Mikrobiol. 1989;144(2):105-9.
1-substituted aminomethyl-3-cyclohexylthiosemicarbazone-2-indolinones (I) were tested for their antibacterial activity against Bacillus pumilis, Bacillus brevis and Bacillus megaterium and antifungal activity against Aspergillus flavus, Aspergillus fumigatus and Aspergillus niger. The majority of the compounds were found to exhibit promising antibacterial and antifungal activities. These compounds were also screened for their antiviral action against tobacco mosaic virus in Nicotiana glutinosa plants in vivo as well as in vitro. Most of the compounds had shown significant antiviral activities both in vivo and in vitro.
对1-取代氨甲基-3-环己基硫代半卡巴腙-2-吲哚酮（I）进行了测试，以考察其对短小芽孢杆菌、短短芽孢杆菌和巨大芽孢杆菌的抗菌活性，以及对黄曲霉、烟曲霉和黑曲霉的抗真菌活性。发现大多数化合物表现出良好的抗菌和抗真菌活性。还对这些化合物在体内和体外针对烟草普通烟草植株中的烟草花叶病毒的抗病毒作用进行了筛选。大多数化合物在体内和体外均显示出显著的抗病毒活性。
