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作为潜在抗菌、抗真菌和抗病毒剂的甲臜和四氮唑盐。

Formazans and tetrazolium salts as potential antibacterial, antifungal, and antiviral agents.

作者信息

Awasthi L P, Singh S P

出版信息

Zentralbl Mikrobiol. 1982;137(6):503-7.

PMID:6817539
Abstract

Fifteen 1-aryl-3-(3'-nitro-4'-methoxyphenyl)-5-phenyl formazans and five 3-aryl-5-(3'-nitro-4'-methoxy phenyl)-2-phenyl tetrazolium bromides have been tested against Escherichia coli and Pseudomonas aeruginosa for their antibacterial and against Aspergillus flavus and Helminthosporium gramineum for their antifungal activities. Most of the compounds have shown promising antibacterial and antifungal action. These compounds were also found to exhibit significant antiviral activity against sunnhemp rosette virus in Cyamopsis tetragonoloba plants in vivo as well as in vivo.

摘要

已对15种1-芳基-3-(3'-硝基-4'-甲氧基苯基)-5-苯基甲腙和5种3-芳基-5-(3'-硝基-4'-甲氧基苯基)-2-苯基溴化四唑进行了测试,检测它们对大肠杆菌和铜绿假单胞菌的抗菌活性,以及对黄曲霉和禾本科长蠕孢的抗真菌活性。大多数化合物显示出有前景的抗菌和抗真菌作用。还发现这些化合物在体内外对四角野豌豆植株中的太阳麻莲座病毒均表现出显著的抗病毒活性。

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