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改良三角形胃十二指肠吻合术在完全腹腔镜下远端胃癌根治术中的应用:一种安全可行的技术

A modified delta-shaped gastroduodenostomy in totally laparoscopic distal gastrectomy for gastric cancer: a safe and feasible technique.

作者信息

Huang Changming, Lin Mi, Chen Qiyue, Lin Jianxian, Zheng Chaohui, Li Ping, Xie Jianwei, Wang Jiabin, Lu Jun

机构信息

Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China.

出版信息

PLoS One. 2014 Jul 14;9(7):e102736. doi: 10.1371/journal.pone.0102736. eCollection 2014.

Abstract

BACKGROUND

The present study introduced a modified delta-shaped gastroduodenostomy (DSG) technique and assessed the safety, feasibility and clinical results of this procedure in patients undergoing totally laparoscopic distal gastrectomy (TLDG) for gastric cancer (GC).

MATERIALS AND METHODS

A total of 102 patients with distal GC undergoing TLDG with modified DSG between January 2013 and December 2013 were enrolled. A retrospective study was performed using a prospectively maintained comprehensive database to evaluate the results of the procedure. Univariate and multivariate analyses were performed to estimate the predictive factors for postoperative morbidity.

RESULTS

The mean operation time was 150.6±30.2 min, the mean anastomosis time was 12.2±4.2 min, the mean blood loss was 48.2±33.2 ml, and the mean times to first flatus, fluid diet, soft diet and postoperative hospital stay were 3.8±1.3 days, 5.0±1.0 days, 7.4±2.1 days and 12.0±6.5 days, respectively. Two patients with minor anastomotic leakage after surgery were managed conservatively; no patient experienced any complications around the anastomosis, such as anastomotic stricture or anastomotic hemorrhage. Univariate analysis showed that age, gastric cancer with hemorrhage and cardiovascular disease combined were significant factors that affected postoperative morbidity (P<0.05). Multivariate analysis found that gastric cancer with hemorrhage was the independent risk factor for the postoperative morbidity (P = 0.042). At a median follow-up of 7 months, no patients had died or experienced recurrent or metastatic disease.

CONCLUSIONS

The modified DSG was technically safe and feasible, with acceptable surgical outcomes, in patients undergoing TLDG for GC, and this procedure may be promising in these patients.

摘要

背景

本研究介绍了一种改良的三角形胃十二指肠吻合术(DSG)技术,并评估了该手术在接受完全腹腔镜远端胃癌切除术(TLDG)治疗胃癌(GC)患者中的安全性、可行性和临床效果。

材料与方法

纳入2013年1月至2013年12月期间102例行改良DSG的TLDG远端GC患者。使用前瞻性维护的综合数据库进行回顾性研究,以评估手术结果。进行单因素和多因素分析以估计术后发病的预测因素。

结果

平均手术时间为150.6±30.2分钟,平均吻合时间为12.2±4.2分钟,平均失血量为48.2±33.2毫升,首次排气、流食、软食和术后住院时间的平均天数分别为3.8±1.3天、5.0±1.0天、7.4±2.1天和12.0±6.5天。两名术后出现轻微吻合口漏的患者经保守治疗;无患者发生吻合口周围任何并发症,如吻合口狭窄或吻合口出血。单因素分析显示,年龄、合并出血的胃癌和心血管疾病是影响术后发病的重要因素(P<0.05)。多因素分析发现,合并出血的胃癌是术后发病的独立危险因素(P = 0.042)。中位随访7个月时,无患者死亡或出现复发或转移性疾病。

结论

改良DSG在接受TLDG治疗GC的患者中技术上安全可行,手术效果可接受,该手术在这些患者中可能具有前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7d6/4096929/2467263f8eee/pone.0102736.g001.jpg

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