Chung Ka-Fai, Yu Branda Yee-Man, Yung Kam-Ping, Yeung Wing-Fai, Ng Tommy H, Ho Fiona Yan-Yee
Department of Psychiatry, The University of Hong Kong, Hong Kong SAR, China.
Compr Psychiatry. 2014 Oct;55(7):1671-8. doi: 10.1016/j.comppsych.2014.06.006. Epub 2014 Jun 13.
There are problems with the fatigue measures currently used in depressed patients. The Multidimensional Fatigue Inventory (MFI-20) covering general fatigue, physical fatigue, mental fatigue, reduced activity and reduced motivation has been widely used in patients with cancer and chronic fatigue syndrome. To address the multidimensional nature of fatigue, we examined the validity and reliability of a Chinese version of the MFI-20 in major depressive disorder (MDD).
Data were derived from a randomized controlled trial of acupuncture in 137 patients with partially remitted MDD. The test-retest reliability, internal consistency, construct and concurrent validity and sensitivity to change of the MFI-20 were analyzed.
The MFI-20 was found to have good internal consistency (Cronbach's alpha=0.89) and 1-week test-retest reliability (Pearson correlation of the total score=0.73). Factor analysis showed 5 factors, but the factor structure was different from that in medical conditions. The 2 most prominent factors, explaining 46% of the total variance, were both associated with physical and mental energy but different in directions. There were adequate concurrent validity and sensitivity to change as evidenced by the significant correlations between the MFI-20 scores and depressive and anxiety symptoms, general health and quality of life.
The Chinese MFI-20 is a valid and reliable instrument for the assessment of fatigue in MDD patients with residual symptoms. The construct of fatigue in MDD seems to be different from that in medical conditions. Further studies are needed to examine the MFI-20 in MDD patients from other cultures.
目前用于抑郁症患者的疲劳测量方法存在问题。多维疲劳量表（MFI - 20）涵盖了一般疲劳、身体疲劳、精神疲劳、活动减少和动力下降等方面，已在癌症和慢性疲劳综合征患者中广泛应用。为了应对疲劳的多维性质，我们检验了中文版MFI - 20在重度抑郁症（MDD）中的有效性和可靠性。
数据来自一项针对137例部分缓解的MDD患者的针刺随机对照试验。分析了MFI - 20的重测信度、内部一致性、结构效度、同时效度以及对变化的敏感性。
发现MFI - 20具有良好的内部一致性（Cronbach's α = 0.89）和1周重测信度（总分的Pearson相关系数 = 0.73）。因子分析显示有5个因子，但因子结构与医学状况中的不同。两个最突出的因子解释了总方差的46%，它们都与身心能量有关，但方向不同。MFI - 20得分与抑郁和焦虑症状、总体健康和生活质量之间存在显著相关性，证明了其有足够的同时效度和对变化的敏感性。
中文版MFI - 20是评估有残留症状的MDD患者疲劳的有效且可靠工具。MDD中疲劳的结构似乎与医学状况中的不同。需要进一步研究来检验其他文化背景下MDD患者的MFI - 20。
