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病毒性下呼吸道感染与早产儿的医疗保健利用情况

Viral lower respiratory tract infections and preterm infants' healthcare utilisation.

作者信息

Drysdale Simon B, Alcazar-Paris Mireia, Wilson Theresa, Smith Melvyn, Zuckerman Mark, Peacock Janet L, Johnston Sebastian L, Greenough Anne

机构信息

Division of Asthma, Allergy and Lung Biology, MRC-Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, UK,

出版信息

Eur J Pediatr. 2015 Feb;174(2):209-15. doi: 10.1007/s00431-014-2380-9. Epub 2014 Jul 19.

Abstract

UNLABELLED

The aim of this study was to determine whether respiratory syncytial virus (RSV) and other viral lower respiratory tract infections (LRTI) in prematurely born infants were associated with similar effects on healthcare utilisation and related cost of care in the second compared to the first year after birth. Thirteen infants who had RSV LRTIs (RSV), 21 who had other viral LRTIs (other viral) and 25 had no viral LRTIs (no LRTI) were prospectively followed. Nasopharyngeal aspirates were collected whenever an infant had an LRTI regardless of whether it was in the hospital or in the community. Healthcare utilisation and the health-related cost of care were determined. Only the RSV group compared to the no LRTI group had higher overall respiratory costs in both year 1 (mean, £3,917 versus £24; p < 0.041) and year 2 (mean, £1,164 versus £61; p = 0.012). Only the RSV group required respiratory admissions; the RSV admission rate in year 2 was 3.4 % (number needed to treat 59).

CONCLUSION

RSV LRTIs are associated with increased healthcare utilisation and cost of care in the first and second year; nevertheless, if prophylaxis is to be cost-effective in the second year, a high risk group needs to be identified.

摘要

未标注

本研究的目的是确定早产婴儿的呼吸道合胞病毒(RSV)和其他病毒性下呼吸道感染(LRTI)与出生后第一年相比,在第二年对医疗保健利用和相关护理成本是否有类似影响。前瞻性随访了13例患有RSV-LRTI的婴儿(RSV组)、21例患有其他病毒性LRTI的婴儿(其他病毒组)和25例未患病毒性LRTI的婴儿(无LRTI组)。无论婴儿是在医院还是社区发生LRTI,均采集鼻咽抽吸物。确定医疗保健利用情况和与健康相关护理成本。仅RSV组与无LRTI组相比,在第1年(均值,3917英镑对24英镑;p<0.041)和第2年(均值,1164英镑对61英镑;p=0.012)的总体呼吸成本均更高。仅RSV组需要呼吸科住院治疗;第2年RSV住院率为3.4%(治疗需59例)。

结论

RSV-LRTI与第一年和第二年医疗保健利用增加及护理成本增加相关;然而,若第二年预防措施要具有成本效益,则需要确定高危人群。

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