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Pancreatoduodenectomy with or without prophylactic falciform ligament wrap around the gastroduodenal artery stump for prevention of pancreatectomy hemorrhage.行或不行预防性镰状韧带包裹胃十二指肠动脉残端的胰十二指肠切除术以预防胰腺切除术后出血。
Trials. 2018 Apr 12;19(1):222. doi: 10.1186/s13063-018-2580-0.

本文引用的文献

1
Use of omentum or falciform ligament does not decrease complications after pancreaticoduodenectomy: nationwide survey of the Japanese Society of Pancreatic Surgery.网膜或镰状韧带的使用并不能降低胰十二指肠切除术后的并发症:日本胰腺外科学会的全国性调查。
Surgery. 2012 Feb;151(2):183-91. doi: 10.1016/j.surg.2011.07.023. Epub 2011 Oct 6.
2
Delayed arterial hemorrhage after pancreaticoduodenectomy: is conservation of hepatic arterial flow vital?胰十二指肠切除术后延迟性动脉出血:保留肝动脉血流至关重要吗?
Pancreas. 2010 Mar;39(2):260-2. doi: 10.1097/MPA.0b013e3181bdc1ff.
3
Measures to prevent pancreatic fistula after pancreatoduodenectomy: a comprehensive review.胰十二指肠切除术后预防胰瘘的措施:一项综述
Arch Surg. 2009 Nov;144(11):1074-80. doi: 10.1001/archsurg.2009.193.
4
Falciform ligament in pancreatoduodenectomy for protection of skeletonized and divided vessels.胰十二指肠切除术中使用镰状韧带保护骨骼化及离断血管。
J Hepatobiliary Pancreat Surg. 2009;16(2):184-8. doi: 10.1007/s00534-008-0036-8. Epub 2009 Jan 24.
5
Modified technique of pancreaticojejunal anastomosis with invagination following pancreaticoduodenectomy: a cohort study.胰十二指肠切除术后采用内翻法的改良胰空肠吻合技术:一项队列研究
World J Surg. 2008 Dec;32(12):2695-700. doi: 10.1007/s00268-008-9760-0.
6
Use of octreotide for the prevention of pancreatic fistula after elective pancreatic surgery: a systematic review and meta-analysis.奥曲肽用于择期胰腺手术后预防胰瘘:一项系统评价和荟萃分析
Can J Surg. 2007 Dec;50(6):459-66.
7
No mortality after 150 consecutive pancreatoduodenctomies with duct-to-mucosa pancreaticogastrostomy.连续150例采用胰管-黏膜胰胃吻合术的胰十二指肠切除术后无死亡病例。
J Surg Oncol. 2008 Mar 1;97(3):205-9. doi: 10.1002/jso.20903.
8
The clinical results of duct-to-mucosa pancreaticojejunostomy after pancreaticoduodenectomy in consecutive 55 cases.连续55例胰十二指肠切除术后胰管-黏膜胰空肠吻合术的临床结果。
Pancreas. 2007 Oct;35(3):273-5. doi: 10.1097/MPA.0b013e3180676dc2.
9
Pancreatic fistula after pancreaticoduodenectomy: a comparison between the two pancreaticojejunostomy methods for approximating the pancreatic parenchyma to the jejunal seromuscular layer: interrupted vs continuous stitches.胰十二指肠切除术后胰瘘:两种使胰腺实质与空肠浆肌层贴合的胰肠吻合方法的比较:间断缝合与连续缝合。
World J Gastroenterol. 2007 Oct 28;13(40):5351-6. doi: 10.3748/wjg.v13.i40.5351.
10
External drainage of pancreatic duct with a stent to reduce leakage rate of pancreaticojejunostomy after pancreaticoduodenectomy: a prospective randomized trial.胰十二指肠切除术后经支架进行胰管外引流以降低胰肠吻合口漏发生率:一项前瞻性随机试验
Ann Surg. 2007 Sep;246(3):425-33; discussion 433-5. doi: 10.1097/SLA.0b013e3181492c28.

在胰十二指肠切除术时包裹胃十二指肠动脉残端可减少术后残端出血的发生率。

"Wrapping the gastroduodenal artery stump" during pancreatoduodenectomy reduced the stump hemorrhage incidence after operation.

机构信息

Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Chang-Hai road 225, Shanghai 200438, China.

出版信息

Chin J Cancer Res. 2014 Jun;26(3):299-308. doi: 10.3978/j.issn.1000-9604.2014.06.08.

DOI:10.3978/j.issn.1000-9604.2014.06.08
PMID:25035657
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4076714/
Abstract

OBJECTIVE

After pancreaticoduodenectomy (PD), the postoperative gastroduodenal artery stump (GDAS) hemorrhage is one of the most serious complications. The purpose of this study is to determine whether wrapping the GDAS during PD could decrease the postoperative GDAS hemorrhage incidence.

METHODS

A retrospective review involving 280 patients who underwent PD from 2005 to 2012 was performed. Wrapping the GDAS during PD was defined as "Wrapping the GDAS using the teres hepatis ligamentum during PD". A total of 140 patients accepted the "wrapping" procedure (wrapping group). The other 140 patients didn't apply the procedure (non-wrapping group). Age, sex, preoperative data, estimated intraoperative blood loss, postoperative complications, pathologic parameters and hospitalization time were compared between two groups.

RESULTS

There were no significant differences in patient characteristics between two groups. After wrapping, the incidence of postoperative GDAS bleeding decreased significantly (1/140 vs. 9/140, P=0.01). The rates of the other complications (such as intra-abdominal infection pancreatic fistula, billiary fistula, gastrointestinal bleeding, et al.) showed no significant differences.

CONCLUSIONS

Wrapping the GDAS during PD significantly reduced the postoperative GDAS hemorrhage incidence. And the "wrapping" had no obvious influence on other complications.

摘要

目的

胰十二指肠切除术后(PD),胃十二指肠动脉残端(GDAS)出血是最严重的并发症之一。本研究旨在确定 PD 过程中包裹 GDAS 是否可以降低术后 GDAS 出血的发生率。

方法

回顾性分析了 2005 年至 2012 年间接受 PD 的 280 例患者。PD 时包裹 GDAS 定义为“PD 时使用肝圆韧带包裹 GDAS”。共有 140 例患者接受了“包裹”手术(包裹组)。另外 140 例患者未进行该手术(非包裹组)。比较两组患者的年龄、性别、术前资料、术中估计出血量、术后并发症、病理参数和住院时间。

结果

两组患者的临床特征无显著差异。包裹后,术后 GDAS 出血的发生率显著降低(1/140 比 9/140,P=0.01)。其他并发症(如腹腔感染、胰瘘、胆瘘、胃肠道出血等)的发生率无显著差异。

结论

PD 过程中包裹 GDAS 可显著降低术后 GDAS 出血的发生率。而且“包裹”对其他并发症没有明显影响。