Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), 1 Department of Thoracic Medical Oncology, 2 Department of Breast Medical Oncology, 3 Department of Lymphoma, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Chin J Cancer Res. 2014 Jun;26(3):355-9. doi: 10.3978/j.issn.1000-9604.2014.06.04.
Synchronous breast cancer and breast lymphoma are rare. It is of high rate of misdiagnosis in clinical practice. Here we present two cases with this presentation. They are both middle-aged women, with stage I invasive ductal carcinoma of the breast. One patient happened to have primary breast lymphoma (PBL); the other was secondary breast lymphoma (SBL). Their pathology and immunohistochemistry (IHC) findings supported the diagnosis of multiple primary carcinoma. Both patients had a surgery. Then they both received CHOP regime chemotherapy and subsequent endocrine therapy.
同步乳腺癌和乳腺淋巴瘤较为罕见，临床上误诊率较高。现报道两例此类患者，均为中年女性，均为 I 期乳腺浸润性导管癌，其中 1 例为原发性乳腺淋巴瘤（PBL），另 1 例为继发性乳腺淋巴瘤（SBL），其病理及免疫组织化学（IHC）检查结果均支持多原发癌诊断。均行手术治疗，术后均接受 CHOP 方案化疗及后续内分泌治疗。
