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胸部计算机断层扫描对钝性创伤所致胸椎损伤的检出率及临床预测因素

Yield and clinical predictors of thoracic spine injury from chest computed tomography for blunt trauma.

作者信息

Langdorf Mark I, Zuabi Nadia, Khan Nooreen A, Bithell Chelsey, Rowther Armaan A, Reed Karin, Anderson Craig L, Lotfipour Shahram, Rodriguez Robert

机构信息

University of California Irvine, Department of Emergency Medicine, Irvine, California.

University of California San Francisco, Department of Emergency Medicine, San Francisco, California.

出版信息

West J Emerg Med. 2014 Jul;15(4):465-70. doi: 10.5811/westjem.2014.4.20672.

Abstract

INTRODUCTION

Cost and radiation risk have prompted intense examination of trauma patient imaging. A proposed decision instrument (DI) for the use of chest computed tomography (CT), (CCT) in blunt trauma patients includes thoracic spine (TS) tenderness, altered mental status (AMS) and distracting painful injury (DPI) as potential predictor variables. TS CT is a separate, costly study whose value is currently ill-defined. The objective of this study is to determine test characteristics of these predictor variables alone, and in combination, to derive a TS injury DI.

METHODS

Prospective cohort study of blunt trauma patients age > 14 in a Level I Trauma Center who had either CCT or TS CT.

RESULTS

Of 1,798 blunt trauma patients, 1,174 (65.3%) had CCT, and 46 (2.6%) had a TS CT at physician discretion. CCT identified 58 TS injuries in 1,220 patients (4.8%). For 1,032 patients without AMS, 18/35 had TS tenderness, for sensitivity of 51.4%, specificity 84.7%, positive (PPV) and negative predictive values (NPV) of 10.5% and 98.0%. Positive likelihood ratio (+LR) was 3.35, with negative (-LR) 0.57. Among the 58 TS injuries, 23 had AMS for sensitivity of 39.7%, with other test characteristics of 85.8%, 12.2%, 96.6%, with +LR 2.79 and -LR 0.70. Thirty-eight of 58 had DPI, for sensitivity 65.5%, with other test characteristics 65.7%, 8.7%, and 97.4%, with +LR 1.91 and -LR 0.52. Combining 3 predictor variables into a proposed DI found 56/58 injuries for test characteristics of 96.6% (95% CI 88.1-99.6%), 49.1% (46.1-52.0%), 8.6% (6.6-11.1%) and 99.7% (CI 98.7-100%), with +LR 1.90 (1.76-2.04) and -LR 0.07 (0.02-0.28). If validated, the DI would exclude 572/1,220 CCT patients from separate TS CT (46.9%, CI 44.1-49.7%), and 141/511 (27.6%, CI 23.8-31.7%) patients who actually had TS CT in our cohort. Medicare payment at our center for sagittal reconstructions of TS CT is $280 for professional plus technical charges ($3,312 per study). The DI, if validated, would save $39,000-$160,000 in TS imaging payments.

CONCLUSION

TS CT is low yield and costly. Patients who are alert, have no TS tenderness and no DPI have a very low likelihood of TS injury (NPV 99.7% 95% CI lower limit 98.7%) with -LR=0.07, 95% CI upper limit 0.28). Avoiding TS CT may save considerable charges and payments.

摘要

引言

成本和辐射风险促使人们对创伤患者的影像学检查进行了深入研究。一种针对钝性创伤患者使用胸部计算机断层扫描(CCT)的拟议决策工具(DI),将胸椎(TS)压痛、精神状态改变(AMS)和分散性疼痛损伤(DPI)作为潜在预测变量。TS CT是一项单独的、成本高昂的检查,其价值目前尚不明确。本研究的目的是确定这些预测变量单独及联合使用时的测试特征,以得出TS损伤DI。

方法

对一级创伤中心年龄大于14岁的钝性创伤患者进行前瞻性队列研究,这些患者接受了CCT或TS CT检查。

结果

在1798例钝性创伤患者中,1174例(65.3%)接受了CCT检查,46例(2.6%)根据医生判断接受了TS CT检查。CCT在1220例患者(4.8%)中发现了58例TS损伤。对于1032例无AMS的患者,35例中有18例有TS压痛,敏感性为51.4%,特异性为84.7%,阳性预测值(PPV)和阴性预测值(NPV)分别为10.5%和98.0%。阳性似然比(+LR)为3.35,阴性似然比(-LR)为0.57。在58例TS损伤中,23例有AMS表现,敏感性为39.7%,其他测试特征分别为85.8%、12.2%、96.6%,+LR为2.79,-LR为0.70。58例中有38例有DPI,敏感性为65.5%,其他测试特征分别为65.7%、8.7%和97.4%,+LR为1.91,-LR为0.52。将3个预测变量组合成一个拟议的DI,发现58例损伤中有56例的测试特征为96.6%(95%CI 88.1 - 99.6%)、49.1%(46.1 - 52.0%)、8.6%(6.6 - 11.1%)和99.7%(CI 98.7 - 100%),+LR为1.90(1.76 - 2.04),-LR为0.07(0.02 - 0.28)。如果得到验证,该DI将使1220例CCT患者中的572例(46.9%,CI 44.1 - 49.7%)无需进行单独的TS CT检查,并且使我们队列中实际接受TS CT检查的511例患者中的141例(27.6%,CI 23.8 - 31.7%)无需进行该项检查。我们中心TS CT矢状面重建的医疗保险支付费用,专业加技术收费为每项280美元(每项研究3312美元)。该DI如果得到验证,将在TS影像学检查支付方面节省39000 - 160000美元。

结论

TS CT的检出率低且成本高。神志清醒、无TS压痛且无DPI的患者发生TS损伤的可能性非常低(NPV 99.7%,95%CI下限98.7%),-LR = 0.07,95%CI上限0.28)。避免进行TS CT检查可能节省大量费用和支出。

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