Rodriguez Robert M, Hendey Gregory W, Mower William, Kea Bory, Fortman Jonathan, Merchant Guy, Hoffman Jerome R
Department of Emergency Medicine, San Francisco General Hospital, University of California, San Francisco, California 94110, USA.
J Trauma. 2011 Sep;71(3):549-53. doi: 10.1097/TA.0b013e3181f2ac9d.
To derive a decision instrument (DI) that identifies patients who have virtually no risk of significant intrathoracic injury (SITI) visible on chest radiography and, therefore, no need for chest imaging.
This is a prospective observational study. At three Level 1 trauma centers, physicians caring for blunt trauma patients aged >14 years were asked to record the presence or absence of 12 clinical criteria before viewing chest imaging results. SITI was defined as pneumothorax, hemothorax, aortic/great vessel injury, two or more rib fractures, ruptured diaphragm, sternal fracture, and pulmonary contusion on official radiograph readings. The κ (interrater reliability) and screening performance of individual criteria were determined. By using recursive partitioning, the most highly sensitive combination of criteria for SITI was derived.
Of the 2,628 subjects enrolled, 271 (10.3%) were diagnosed with a total of 462 SITIs, with rib fractures (73%), pneumothorax (38%), and pulmonary contusion (29%) as the most common injuries. Chest pain and chest wall tenderness had the highest sensitivity for SITI (65%). The DI of chest pain, distracting injury, chest wall tenderness, intoxication, age >60 years, rapid deceleration, and altered alertness/mental status had the following screening performance: sensitivity 99.3% (95% confidence interval [CI], 97.4-99.8), specificity 14.0% (95% CI, 12.6-15.4), negative predictive value 99.4% (95% CI, 97.8-99.8), and positive predictive value 11.7% (95% CI, 10.5-13.1). All seven criteria in the DI met the predetermined cut off for acceptable κ (range, 0.51-0.81).
We derived a DI consisting of seven clinical criteria that can identify SITI in blunt trauma patients with extremely high sensitivity. If validated, this instrument will allow for safe, selective chest imaging with potential resource savings.
推导一种决策工具(DI),用于识别胸部X线片上几乎没有严重胸内损伤(SITI)风险、因此无需进行胸部影像学检查的患者。
这是一项前瞻性观察性研究。在三个一级创伤中心,要求负责护理年龄大于14岁的钝性创伤患者的医生在查看胸部影像学检查结果之前记录12项临床标准的有无。SITI被定义为气胸、血胸、主动脉/大血管损伤、两根或更多肋骨骨折、膈肌破裂、胸骨骨折以及官方X线片读片中的肺挫伤。确定了各标准的κ值(评分者间信度)和筛查性能。通过递归划分,得出了对SITI敏感性最高的标准组合。
在纳入的2628名受试者中,271名(10.3%)被诊断出共有462处SITI,其中肋骨骨折(73%)、气胸(38%)和肺挫伤(29%)是最常见的损伤。胸痛和胸壁压痛对SITI的敏感性最高(65%)。胸痛、分散性损伤、胸壁压痛、中毒、年龄>60岁、快速减速以及意识/精神状态改变的DI具有以下筛查性能:敏感性99.3%(95%置信区间[CI],97.4 - 99.8),特异性14.0%(95% CI,12.6 - 15.4),阴性预测值99.4%(95% CI,97.8 - 99.8),阳性预测值11.7%(95% CI,10.5 - 13.1)。DI中的所有七项标准均符合可接受κ值的预定截断值(范围为0.51 - 0.81)。
我们推导了一种由七项临床标准组成的DI,该标准能够以极高的敏感性识别钝性创伤患者中的SITI。如果得到验证,该工具将允许进行安全、有选择性的胸部影像学检查,并可能节省资源。