Shah A, Behera S, Panjabi C
Department of Respiratory Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi 110 007, India. E-mail:
Department of Respiratory Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi 110 007, India.
Eur Ann Allergy Clin Immunol. 2014 Jul;46(4):147-51.
Allergic bronchopulmonary aspergillosis (ABPA) is a disease predominantly seen in susceptible asthmatic subjects, due to a hypersensitivity phenomenon caused by colonisation of the airways by Aspergillus species. Although collapse, both lobar and segmental due to mucoid impaction, is not uncommon in ABPA, a middle lobe syndrome (MLS) secondary to ABPA is rather an uncommon association. We report this rare and unusual clinical presentation in a 36-year-old male, who presented for evaluation of a "non resolving pneumonia". Imaging suggested the presence of a MLS and central bronchiectasis. Further investigations revealed that the patient met 6/8 of the essential diagnostic criteria for ABPA. Appropriate therapy with oral corticosteroids resulted in remarkable symptomatic improvement.
变应性支气管肺曲霉菌病(ABPA)是一种主要见于易患哮喘的患者的疾病,由曲霉菌属在气道定植引起的超敏反应现象所致。虽然在ABPA中,由于黏液嵌塞导致的肺叶和肺段萎陷并不少见,但ABPA继发的中叶综合征(MLS)却是一种相当罕见的关联情况。我们报告了一名36岁男性患者这种罕见且不寻常的临床表现,该患者因“迁延不愈的肺炎”前来评估。影像学检查提示存在MLS和中央型支气管扩张。进一步检查发现该患者符合ABPA的8项主要诊断标准中的6项。口服糖皮质激素的适当治疗使症状得到显著改善。