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[杨桃作为急性肾损伤的一个病因]

[Star fruit as a cause of acute kidney injury].

作者信息

Scaranello Karilla Lany, Alvares Valeria Regina de Cristo, Carneiro Daniely Maria Queiroz, Barros Flávio Henrique Soares, Gentil Thais Marques Sanches, Thomaz Myriam José, Pereira Benedito Jorge, Pereira Mariana Batista, Leme Graziella Malzoni, Diz Mary Carla Esteves, Laranja Sandra Maria Rodrigues

机构信息

Hospital do Servidor Público Estadual.

出版信息

J Bras Nefrol. 2014 Apr-Jun;36(2):246-9. doi: 10.5935/0101-2800.20140036.

DOI:10.5935/0101-2800.20140036
PMID:25055366
Abstract

The star fruit belongs to the family Oxalidacea, species Averrhoa carambola. It is rich in minerals, vitamin A, C, B complex vitamins and oxalic acid. Recent studies show that the toxicity of the fruit differs between the patients and may be explained by single biological responses, age, and the intake quantity of the neurotoxin in each fruit in addition to glomerular filtration rate given by each patient. Additionally, the nephrotoxicity caused by the fruit is dose-dependent and may lead to the deposition of crystals of calcium oxalate intratubular, as well as by direct injury to the renal tubular epithelium, leading to apoptosis of the same. We report the case of a patient who after ingestion of the juice and fresh fruit, developed acute renal failure requiring dialysis, evolving with favourable outcome and recovery of renal function.

摘要

杨桃属于酢浆草科,学名为阳桃。它富含矿物质、维生素A、C、复合维生素B和草酸。最近的研究表明,该水果对不同患者的毒性存在差异,这可能是由个体生物学反应、年龄、每个水果中神经毒素的摄入量以及每位患者的肾小球滤过率所导致的。此外,该水果引起的肾毒性具有剂量依赖性,可能导致草酸钙晶体在肾小管内沉积,以及对肾小管上皮细胞的直接损伤,进而导致肾小管上皮细胞凋亡。我们报告了一例患者,该患者在饮用杨桃汁并食用新鲜杨桃后,出现了需要透析的急性肾衰竭,最终肾功能良好恢复。

相似文献

1
[Star fruit as a cause of acute kidney injury].[杨桃作为急性肾损伤的一个病因]
J Bras Nefrol. 2014 Apr-Jun;36(2):246-9. doi: 10.5935/0101-2800.20140036.
2
Acute Kidney Injury Following Star Fruit Ingestion: A Case Series.杨桃摄入后急性肾损伤:病例系列
Wilderness Environ Med. 2021 Mar;32(1):98-101. doi: 10.1016/j.wem.2020.11.003. Epub 2021 Jan 29.
3
Star fruit toxicity: a cause of both acute kidney injury and chronic kidney disease: a report of two cases.杨桃中毒:急性肾损伤和慢性肾脏病的一个病因:两例报告
BMC Res Notes. 2015 Dec 17;8:796. doi: 10.1186/s13104-015-1640-8.
4
Mechanisms of star fruit (Averrhoa carambola) toxicity: A mini-review.杨桃毒性的作用机制:小型综述。
Toxicon. 2020 Nov;187:198-202. doi: 10.1016/j.toxicon.2020.09.010. Epub 2020 Sep 20.
5
Nephrotoxicity and neurotoxicity following star fruit (Averrhoa carambola) ingestion: a narrative review.食用杨桃(Averrhoa carambola)后引起的肾毒性和神经毒性:综述。
Trans R Soc Trop Med Hyg. 2021 Sep 3;115(9):947-955. doi: 10.1093/trstmh/trab026.
6
Star fruit nephrotoxicity: a case series and literature review.杨桃肾毒性:病例系列及文献复习。
BMC Nephrol. 2018 Oct 22;19(1):288. doi: 10.1186/s12882-018-1084-1.
7
N-acetylcysteine protects against star fruit-induced acute kidney injury.N-乙酰半胱氨酸可预防杨桃诱导的急性肾损伤。
Ren Fail. 2017 Nov;39(1):193-202. doi: 10.1080/0886022X.2016.1256315. Epub 2016 Nov 15.
8
Toxicity of star fruit () in renal patients: A systematic review of the literature.杨桃对肾病患者的毒性:文献系统综述
Saudi J Kidney Dis Transpl. 2017 Jul-Aug;28(4):709-715.
9
Star fruit as a cause of acute kidney injury: a case report.
J Bras Nefrol. 2014 Apr-Jun;36(2):118-20. doi: 10.5935/0101-2800.20140019.
10
Acute oxalate nephropathy after ingestion of star fruit.食用杨桃后发生的急性草酸盐肾病。
Am J Kidney Dis. 2001 Feb;37(2):418-22. doi: 10.1053/ajkd.2001.21333.

引用本文的文献

1
Standardization of experimental model regarding star fruit intoxication in Wistar rats suffering with nephropathy.标准化实验模型,观察肾病 Wistar 大鼠杨桃中毒情况。
Acta Cir Bras. 2021 Feb 22;36(2):e360204. doi: 10.1590/ACB360204. eCollection 2021.
2
Acute Kidney Injury with Neurological Features: Beware of the Star Fruit and its Caramboxin.伴有神经学特征的急性肾损伤:小心杨桃及其毒素。
Indian J Nephrol. 2020 Jan-Feb;30(1):42-46. doi: 10.4103/ijn.IJN_53_19. Epub 2019 Dec 27.
3
Neurotoxicity following the Ingestion of Bilimbi Fruit () in an End-Stage Renal Disease Patient on Hemodialysis.
一名接受血液透析的终末期肾病患者摄入罗望子果实后的神经毒性。
Case Rep Nephrol Dial. 2017 Jan 20;7(1):6-12. doi: 10.1159/000454945. eCollection 2017 Jan-Apr.