Tryggestad Jeanie B, Short Kevin R
Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK.
Exerc Sport Sci Rev. 2014 Oct;42(4):175-82. doi: 10.1249/JES.0000000000000024.
Recent work showed that arterial compliance may be elevated unexpectedly in obese children, attributable to accelerated growth and maturation. We hypothesize that children with obesity or Type 2 diabetes may reach peak arterial maturation earlier in life and then experience an earlier, and potentially more rapid, decline in arterial compliance, leading toward earlier cardiovascular disease development.
最近的研究表明,肥胖儿童的动脉顺应性可能会意外升高,这归因于生长加速和成熟加快。我们假设,肥胖或2型糖尿病儿童可能在生命早期就达到动脉成熟的峰值,然后动脉顺应性出现更早且可能更快的下降,从而导致心血管疾病更早发生。