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儿童意外摄入腐蚀性物质导致的局部损伤。

Local injuries by accidental ingestion of corrosive substances by children.

作者信息

Mühlendahl K E, Oberdisse U, Krienke E G

出版信息

Arch Toxicol. 1978 Feb 14;39(4):299-314. doi: 10.1007/BF00296389.

Abstract

Own data and analysis of previous publications show that situations where accidental ingestion of corrosive substances by children may have happened are frequent, but severe corrosive esophagitis leading to perforation or stricture formation is very rare. In case of suspected esophageal injury, esophagoscopy and glucocorticoid treatment become necessary. The evaluation of the initial symptoms in patients from our own material and from the literature indicates that all children with serious esophageal burns had one or more of the following symptoms: visible burns in the oral cavity, hypersalivation, retching, vomiting, retrosternal or epigastric pain, cardiovascular collaps, airway stenosis. Hence, children with an uncertain history of ingestion and without any of these symptoms need not be treated. After ingestion of liquid substances, but never of dry or granular products, lesions in the esophagus without accompanying burns in the oral cavity were observed. The evaluation of 1158 cases of accidental ingestions of several types of household products and a collection of data from the literature on the causticity of these substances shows that cleaners containing mainly detergents and phosphates (with pH values generally between 9 and 11), and household bleaches on sodium hypochlorite basis, are relatively harmless. Drain cleaners (NaOH), decalcifiers (formic acid) and detergents for automatic dish washing machines (metasilicates) are very caustic and are responsible for the majority of serious accidents in children.

摘要

我们自己的数据以及对既往出版物的分析表明,儿童意外摄入腐蚀性物质的情况很常见,但导致穿孔或狭窄形成的严重腐蚀性食管炎非常罕见。在怀疑有食管损伤的情况下,食管镜检查和糖皮质激素治疗是必要的。对我们自己收集的病例资料以及文献中患者初始症状的评估表明,所有严重食管烧伤的儿童都有以下一种或多种症状:口腔可见烧伤、流涎过多、干呕、呕吐、胸骨后或上腹部疼痛、心血管虚脱、气道狭窄。因此,摄入史不明且无上述任何症状的儿童无需治疗。摄入液体物质后,但绝不是干燥或颗粒状产品后,观察到食管有损伤而口腔无伴随烧伤的情况。对1158例意外摄入几种家用产品的病例评估以及从文献中收集的关于这些物质腐蚀性的数据表明,主要含有洗涤剂和磷酸盐(pH值一般在9至11之间)的清洁剂以及次氯酸钠基家用漂白剂相对无害。排水清洁剂(氢氧化钠)、除垢剂(甲酸)和自动洗碗机用洗涤剂(偏硅酸盐)腐蚀性很强,是导致儿童大多数严重事故的原因。

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