Nagaraja Vivek, Denton Christopher P, Khanna Dinesh
Division of Rheumatology, University of Michigan, Ann Arbor, MI, USA and.
Division of Medicine, University College London, London, UK.
Rheumatology (Oxford). 2015 Nov;54(11):1944-53. doi: 10.1093/rheumatology/keu285. Epub 2014 Jul 26.
SSc is a multiorgan disease with significant morbidity that is associated with poor health-related quality of life. Treatment of this condition is often organ based and non-curative. However, there are newer, potentially disease-modifying therapies available to treat certain aspects of the disease. This review focuses on old and new therapies in the management of SSc in clinical practice.
系统性硬化症是一种多器官疾病,发病率高,与健康相关生活质量差有关。这种疾病的治疗通常基于器官,且无法治愈。然而,有一些新的、可能改变疾病进程的疗法可用于治疗该疾病的某些方面。本综述聚焦于临床实践中系统性硬化症管理方面的新旧疗法。