Niimi M, Takahara J, Sato M, Kawanishi K
Department of Clinical Laboratory, Kagawa Medical School, Japan.
Peptides. 1989 May-Jun;10(3):605-8. doi: 10.1016/0196-9781(89)90150-2.
The topographical location of neurons containing GRF which project to the median eminence were studied with immunofluorescence for GRF in combination with the retrograde transport of True blue. After the injection of True blue into the median eminence, retrogradely-labeled GRF neurons were identified in the arcuate nucleus and the lateral basal hypothalamus. GRF neurons in the perifornical area contained no positive dye. We concluded that the location of neurons containing hypophysiotrophic GRF are confined within the arcuate nucleus and the lateral basal hypothalamus.
采用免疫荧光法结合真蓝逆行转运技术，研究了投射至正中隆起的含生长激素释放因子（GRF）神经元的拓扑位置。将真蓝注入正中隆起后，在弓状核和下丘脑外侧基底部发现了逆行标记的GRF神经元。穹窿周区的GRF神经元未发现阳性染料。我们得出结论，含促垂体生长激素释放因子的神经元位于弓状核和下丘脑外侧基底部。
