Bethesda and Baltimore, Md.; Pittsburgh, Pa.; and Fort Belvoir, Va. From the Walter Reed National Military Medical Center; Department of Plastic and Reconstructive Surgery, University of Pittsburgh Medical Center; Department of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine; Uniformed Services University of Health Sciences; and Fort Belvoir Community Hospital.
Plast Reconstr Surg. 2014 Aug;134(2):333-338. doi: 10.1097/PRS.0000000000000363.
Extremity battlefield injuries from Operation Iraq and Enduring Freedom (Afghanistan) requiring multiple limbs salvaged with tissue transfers in the same patient are an understudied population. This study aimed to report the limb salvage outcomes in patients requiring multiple flap procedures for two or more concurrent extremity injuries.
A retrospective cohort comparison of warfare-related extremity injuries treated for limb salvage from 2003 through 2012 at the National Capital Consortium was completed. Number of single and multiple flap limb salvages, Injury Severity Score, success rates, and complications were analyzed.
A total of 359 limb salvage reconstructive procedures were performed, consisting of 311 cases of single extremity salvage and 48 cases of multiple flap or multiple extremity salvage. The Injury Severity Score was significantly higher in the multiple extremity group (23) than in the single extremity group (17; p<0.001). Primary flap failure rate was 9 percent in single and 12 percent in multiple limb salvage cases (p=0.390). The subgroup flap failure rate in the multiple limb salvage cohort was 8 percent, 7 percent, and 25 percent for pedicle flaps, pedicle/free flaps, and free flaps, respectively (p=0.361). The total complication rate was 26 percent and 33 percent for single and multiple limb salvage cases, respectively (p=0.211).
Limb salvage requiring multiple flap procedures in the polyextremity-injured patent is safe and equally effective when compared with a single-limb-injured cohort despite a significantly higher injury severity score. Overall complication rates were not significantly different, although subgroup analysis demonstrated a trend toward increased flap failure in the multiple free flap cohort.
CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, III.
在同一患者中进行多次肢体挽救性组织转移以治疗来自伊拉克和持久自由行动(阿富汗)的四肢战场损伤是一个研究较少的人群。本研究旨在报告需要两次或更多次同时发生的四肢损伤进行多次皮瓣手术的患者的肢体挽救结局。
对 2003 年至 2012 年期间在国家首都联盟接受肢体挽救治疗的与战争相关的四肢损伤进行回顾性队列比较。分析了单次和多次皮瓣肢体挽救的数量、损伤严重程度评分、成功率和并发症。
共进行了 359 次肢体挽救重建手术,包括 311 例单肢挽救和 48 例多皮瓣或多肢挽救。多肢组的损伤严重程度评分明显高于单肢组(23 对 17;p<0.001)。单次和多次肢体挽救病例的原发性皮瓣失败率分别为 9%和 12%(p=0.390)。多肢挽救队列中,亚组皮瓣失败率分别为 8%、7%和 25%,用于带蒂皮瓣、带蒂/游离皮瓣和游离皮瓣(p=0.361)。总的并发症发生率分别为 26%和 33%,用于单肢和多肢挽救病例(p=0.211)。
与单肢损伤患者相比,多肢损伤患者需要进行多次皮瓣手术是安全且同样有效的,尽管损伤严重程度评分明显较高。总体并发症发生率无显著差异,但亚组分析显示,多次游离皮瓣组皮瓣失败的趋势增加。
临床问题/证据水平:治疗,III 级。