Manea A, Nechifor M
Rev Med Chir Soc Med Nat Iasi. 2014 Apr-Jun;118(2):439-49.
The purpose of this study was to determine whether chronic periodontitis can stand behind modifications in the salivary and blood concentration of some bivalent cations (Calcium, Magnesium, Zinc and Copper). For this purpose, we formed a group of 30 adult patients with clinically onset chronic periodontitis, and another one of 30 healthy patients as control. Both groups were free from acute oral pathology and general illnesses. The groups were divided again according to the habit of smoking. Total saliva samples were obtained as "first time in the morning", then weighed and processed. Cations were read on Atomic Absorption Spectrophotometer and by Ion Chromatography (Magnesium). The same patients were required to undergo laboratory blood tests for Calcium, Magnesium and Zinc. Data obtained was normalised, then statistically interpreted using two-tailed heteroscedastic t-Student tests. Our data confirmed the existence of a connection between salivary calcium, magnesium, zinc and copper, and of blood magnesium, and chronic periodontitis. Salivary calcium and magnesium are affected by smoking.
本研究的目的是确定慢性牙周炎是否与某些二价阳离子(钙、镁、锌和铜)的唾液及血液浓度变化有关。为此,我们组建了一组30名临床确诊为慢性牙周炎的成年患者,以及另一组30名健康患者作为对照。两组患者均无急性口腔病变及全身性疾病。根据吸烟习惯,两组又进一步细分。采集两组患者“晨起首次”的全唾液样本,称重后进行处理。采用原子吸收分光光度计和离子色谱法(测定镁)读取阳离子含量。要求相同的这些患者进行血液中钙、镁和锌的实验室检测。对所获数据进行标准化处理,然后使用双尾异方差t检验进行统计学解释。我们的数据证实唾液中的钙、镁、锌和铜以及血液中的镁与慢性牙周炎之间存在关联。唾液中的钙和镁受吸烟影响。