Hughes Kakra, Boyd Christopher, Oyetunji Tolulope, Tran Daniel, Chang David, Rose David, Siram Suryanarayan, Cornwell Edward, Obisesan Thomas
Department of Surgery, Howard University, Washington, DC, USA
Department of Surgery, Howard University, Washington, DC, USA.
Vasc Endovascular Surg. 2014 Jul-Aug;48(5-6):402-5. doi: 10.1177/1538574414543276. Epub 2014 Jul 30.
Previous reports have suggested that black patients have a higher rate of major lower extremity amputation and a lower rate of revascularization for limb salvage when compared to white patients.
We undertook this study to determine the extent of this ethnic disparity in recent years and to evaluate whether the widespread adoption of endovascular techniques has had an impact on this disparity.
The American College of Surgeons' National Surgical Quality Improvement Program (NSQIP) database was queried to identify all patients who had undergone an above- or below-knee amputation as well as all patients who had undergone an open or endovascular revascularization procedure for critical limb ischemia for the years 2005 to 2006. Patient demographics and 30-day outcomes were recorded, and comparisons were made among the different ethnic groups.
There were 1568 patients identified in the NSQIP database as having undergone a major lower extremity amputation in 2005 and 2006. Of these patients, 54% were white, 29% black, 8% Hispanic, and 0.7% Asian. Eight percent of patients did not have identifying ethnic data. The group undergoing amputation was primarily male (61%) with a mean age of 65. Median length of stay was 11 days, and 30-day mortality was 9% following amputation. During this same time period, 4191 patients underwent an open surgical procedure and 569 patients underwent an endovascular procedure for the purposes of limb salvage. Of those patients undergoing an open procedure, 74% were white, 12% black, 4% Hispanic, 0.4% Asian, and 10% did not have identifying ethnic data. Open surgical patients were primarily male (63%) with a mean age of 66. Median length of stay was 6 days, and 30-day mortality was 3.3%. Of those patients undergoing an endovascular procedure, 79% were white, 10% black, 2% Hispanic, 1% Asian, and 8% did not have identifying ethnic data. The endovascular group was also primarily male (61%) with a mean age of 68. Median length of stay was 5 days, and 30-day mortality was 4%.
There remains a significant ethnic disparity in limb-salvage revascularization. Blacks comprise 29% of patients undergoing a major lower extremity amputation, but only 12% of those undergoing an open surgical procedure and 10% of those undergoing an endovascular procedure for limb salvage. The widespread adoption of endovascular revascularization techniques appears not to have had much impact on this disparity.
先前的报告表明,与白人患者相比,黑人患者下肢大截肢的发生率更高,而肢体挽救性血管重建的发生率更低。
我们开展这项研究以确定近年来这种种族差异的程度,并评估血管内技术的广泛应用是否对这种差异产生了影响。
查询美国外科医师学会国家外科质量改进计划(NSQIP)数据库,以识别2005年至2006年期间所有接受过膝上或膝下截肢的患者以及所有因严重肢体缺血接受开放或血管内血管重建手术的患者。记录患者人口统计学资料和30天结局,并在不同种族群体之间进行比较。
NSQIP数据库中识别出1568例患者在2005年和2006年接受了下肢大截肢手术。在这些患者中,54%为白人,29%为黑人,8%为西班牙裔,0.7%为亚裔。8%的患者没有可识别的种族数据。接受截肢手术的群体主要为男性(61%),平均年龄为65岁。中位住院时间为11天,截肢后30天死亡率为9%。在同一时期,4191例患者接受了开放手术,569例患者接受了血管内手术以挽救肢体。在接受开放手术的患者中,74%为白人,12%为黑人,4%为西班牙裔,0.4%为亚裔,10%没有可识别的种族数据。接受开放手术的患者主要为男性(63%),平均年龄为66岁。中位住院时间为6天,30天死亡率为3.3%。在接受血管内手术的患者中,79%为白人,10%为黑人,2%为西班牙裔,1%为亚裔,8%没有可识别的种族数据。血管内手术组也主要为男性(61%),平均年龄为68岁。中位住院时间为5天,30天死亡率为4%。
在肢体挽救性血管重建方面仍存在显著的种族差异。黑人占接受下肢大截肢手术患者的29%,但仅占接受开放手术挽救肢体患者的12%以及接受血管内手术挽救肢体患者的10%。血管内血管重建技术的广泛应用似乎对这种差异没有太大影响。