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破裂性腹主动脉瘤治疗中的种族差异。

Racial disparities in treatment of ruptured abdominal aortic aneurysms.

机构信息

Division of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Boston, MA.

Division of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Boston, MA.

出版信息

J Vasc Surg. 2023 Feb;77(2):406-414. doi: 10.1016/j.jvs.2022.08.009. Epub 2022 Aug 18.

Abstract

OBJECTIVE

The Society for Vascular Surgery has recommended immediate transfer of patients with ruptured abdominal aortic aneurysms (rAAAs) to a regional center when feasible. However, Black patients might be less likely to be transferred and more likely to be turned down for repair. We, therefore, examined the transfer rates, turndown rates, and outcomes for Black vs White patients presenting with rAAAs in two large databases.

METHODS

We examined all rAAA repairs in the Vascular Quality Initiative from 2003 to 2020 to evaluate the transfer rates and outcomes for Black vs White patients. We used the National Inpatient Sample from 2004 to 2015 to examine the turndown rates. Mixed effects logistic regression, Cox regression, and marginal effects modeling were used to study the interaction between race, insurance status, surgery type (open repair vs endovascular aortic aneurysm repair), and hospital volume.

RESULTS

We identified 4935 patients with rAAAs in the Vascular Quality Initiative (6.2% Black) and 48,489 in the National Inpatient Sample (6.0% Black). The rates of transfer were high; however, Black patients were significantly less likely to undergo transfer before repair compared with White patients (49% Black vs 62% White; P = .002). The result was consistent in both crude and adjusted analyses when considering only stable patients and was not modified by insurance status, surgery type, or hospital volume. No significant differences were found in perioperative mortality (22% vs 26%; P = .098) or complications (52% vs 52%; P = .64). However, Black patients were significantly more likely to be turned down for repair (37% vs 28%; odds ratio, 1.5; 95% confidence interval, 1.2-1.9; P < .001). A significant interaction was found between race and insurance status with respect to turndown. Patients with private insurance had undergone surgery at a similar rate, regardless of race. However, among patients with Medicare or Medicaid/self-pay, Black patients were less likely than were White patients to undergo repair (Medicare, 64% vs 72%; P = .001; Medicaid/self-pay, 43% vs 61%; P = .031). Patients with Medicaid/self-pay were also less likely to undergo repair than were patients of the same race with either Medicare or private insurance (P < .05).

CONCLUSIONS

We found that Black patients with rAAAs are poorly served by the current systems of interhospital transfer in the United States, because they less often undergo transfer before repair. Although the postoperative outcomes appeared similar, this finding could be falsely optimistic, because Black patients, especially the underinsured, were turned down for repair more often even after adjustment. Significant work is needed to better understand the reasons underlying these disparities and identify the targets to improve the care of Black patients with rAAAs.

摘要

目的

血管外科学会建议,一旦患者出现破裂性腹主动脉瘤(rAAA),应尽可能将其立即转至区域中心。然而,黑人患者可能不太可能被转院,而且更有可能被拒绝接受修复手术。因此,我们在两个大型数据库中检查了 rAAA 黑人患者与白人患者的转院率、拒绝率和结局。

方法

我们对 2003 年至 2020 年血管质量倡议中的所有 rAAA 修复进行了检查,以评估黑人患者与白人患者的转院率和结局。我们使用了 2004 年至 2015 年的国家住院患者样本,以检查拒绝率。使用混合效应逻辑回归、Cox 回归和边际效应模型来研究种族、保险状况、手术类型(开放修复与血管内主动脉瘤修复)和医院容量之间的相互作用。

结果

我们在血管质量倡议中确定了 4935 例 rAAA 患者(6.2%为黑人)和国家住院患者样本中的 48489 例(6.0%为黑人)。转院率很高;然而,与白人患者相比,黑人患者在接受修复前接受转院的可能性明显较小(49%黑人 vs 62%白人;P =.002)。在仅考虑稳定患者的情况下,这一结果在未经调整和调整后的分析中都是一致的,且不受保险状况、手术类型或医院容量的影响。围手术期死亡率(22% vs 26%;P =.098)或并发症(52% vs 52%;P =.64)均无显著差异。然而,黑人患者被拒绝修复的可能性明显更高(37% vs 28%;优势比,1.5;95%置信区间,1.2-1.9;P <.001)。种族和保险状况之间存在显著的相互作用,影响拒绝修复的概率。无论种族如何,私人保险患者接受手术的比例相似。然而,在医疗保险或医疗补助/自付费用的患者中,黑人患者接受修复的可能性低于白人患者(医疗保险,64% vs 72%;P =.001;医疗补助/自付费用,43% vs 61%;P =.031)。与同样有医疗保险或私人保险的同种族患者相比,医疗补助/自付费用的患者接受修复的可能性也更低(P <.05)。

结论

我们发现,美国目前的医院间转院系统对黑人 rAAA 患者服务不佳,因为他们在接受修复前转院的可能性较小。尽管术后结局似乎相似,但这一发现可能过于乐观,因为即使在调整后,黑人患者,尤其是保险不足的患者,因各种原因被拒绝修复的几率更高。需要开展大量工作,以更好地了解造成这些差异的原因,并确定改善黑人 rAAA 患者护理的目标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a492/9868053/17c8d3127b80/nihms-1830348-f0001.jpg

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