Wall Geoffrey C, Bryant Ginelle A, Bottenberg Michelle M, Maki Erik D, Miesner Andrew R
Geoffrey C Wall, Ginelle A Bryant, Michelle M Bottenberg, Erik D Maki, Andrew R Miesner, Department of Pharmacy Practice, Drake University College of Pharmacy, Des Moines, IA 50311, United States.
World J Gastroenterol. 2014 Jul 21;20(27):8796-806. doi: 10.3748/wjg.v20.i27.8796.
Irritable bowel syndrome (IBS) is one of the most common gastrointestinal disorders causing patients to seek medical treatment. It is relatively resource intensive and the source of significant morbidity. Recent insights into the pathophysiology and treatment of IBS has given clinicians more options than ever to contend with this disorder. The purpose of our paper is to review older, "classic" treatments for IBS as well as newer agents and "alternative" therapies. We discuss the evidence base of these drugs and provide context to help develop appropriate treatment plans for IBS patients.
肠易激综合征(IBS)是导致患者寻求医疗救治的最常见胃肠道疾病之一。它相对耗费资源,且是严重发病的根源。最近对肠易激综合征病理生理学和治疗的深入了解,为临床医生应对这种疾病提供了比以往更多的选择。我们论文的目的是回顾针对肠易激综合征的较老的“经典”治疗方法以及新药物和“替代”疗法。我们讨论这些药物的证据基础,并提供相关背景信息,以帮助为肠易激综合征患者制定合适的治疗方案。