Loi Pasqualino, Saragusty Joseph, Ptak Grazyna
Department of Comparative Biomedical Sciences, University of Teramo, Piazza Aldo Moro 45, Teramo, 64100, Italy,
Adv Exp Med Biol. 2014;753:489-502. doi: 10.1007/978-1-4939-0820-2_19.
Recently there has been growing interest in applying the most advanced embryological tools, particularly cloning, to bring extinct species back to life, with a particular focus on the woolly mammoth (Mammuthus primigenius). Mammoth's bodies found in the permafrost are relatively well preserved, with identifiable nuclei in their tissues. The purpose of this chapter is to review the literature published on the topic, and to present the strategies potentially suitable for a mammoth cloning project, with a frank assessment of their feasibility and the ethical issues involved.
最近,人们对应用最先进的胚胎学工具,尤其是克隆技术,使灭绝物种复活的兴趣日益浓厚,其中特别关注猛犸象(长毛猛犸象)。在永久冻土中发现的猛犸象尸体保存相对完好,其组织中的细胞核可识别。本章的目的是回顾关于该主题已发表的文献,并提出可能适用于猛犸象克隆项目的策略,同时坦率评估其可行性及所涉及的伦理问题。