Alameddine Ramzi M, Mansour Ahmad M, Kahtani Eman
Department of Ophthalmology, American University of Beirut, Beirut, Lebanon.
King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Middle East Afr J Ophthalmol. 2014 Jul-Sep;21(3):244-50. doi: 10.4103/0974-9233.134686.
Choroidal osteomas are rare benign ossifying tumors that appear as irregular slightly elevated, yellow-white, juxtapapillary, choroidal mass with well-defined geographic borders, depigmentation of the overlying pigment epithelium; and with multiple small vascular networks on the tumor surface. Visual loss results from three mechanisms: Atrophy of the retinal pigment epithelium overlying a decalcified osteoma; serous retinal detachment over the osteoma from decompensated retinal pigment epithelium, and most commonly from choroidal neovascularization. Recent evidence points to the beneficial effects of intravitreal vascular endothelial growth factor antagonists in improving visual acuity in serous retinal detachment with or without choroidal neovascularization.
脉络膜骨瘤是罕见的良性骨化性肿瘤，表现为不规则的轻度隆起、黄白色、邻近视乳头的脉络膜肿物，边界清晰呈地图状，上方色素上皮脱色素；肿瘤表面有多个小血管网。视力丧失由三种机制导致：覆盖脱钙骨瘤的视网膜色素上皮萎缩；视网膜色素上皮失代偿导致骨瘤上方的浆液性视网膜脱离，最常见的是脉络膜新生血管形成。最近的证据表明，玻璃体内血管内皮生长因子拮抗剂对改善伴有或不伴有脉络膜新生血管的浆液性视网膜脱离患者的视力有益。
