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脉络膜骨瘤

Choroidal osteoma.

作者信息

Kadrmas E F, Weiter J J

机构信息

Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston 02114, USA.

出版信息

Int Ophthalmol Clin. 1997 Fall;37(4):171-82. doi: 10.1097/00004397-199703740-00015.

DOI:10.1097/00004397-199703740-00015
PMID:9429940
Abstract

The choroidal osteoma is a benign, ossifying tumor of the choroid that typically is found in young, healthy women in the second or third decade of life. Its pathogenesis is unknown. This tumor is clinically unilateral in 75% of cases and tends to be located in the juxtapapillary region. Choroidal neovascularization may occur in up to one-third of cases. The choroidal osteoma must be differentiated from other intraocular tumors as well as cases of dystrophic and metastatic calcification. Ultrasonography and computed tomography may help in the diagnosis by demonstrating a calcified plaque at the level of the choroid. Fluorescein angiography and ICG videoangiography may demonstrate choroidal neovascularization, which may be amenable to treatment by laser photocoagulation.

摘要

脉络膜骨瘤是一种脉络膜的良性骨化性肿瘤,多见于20至30岁的年轻健康女性。其发病机制尚不清楚。该肿瘤75%的病例临床上为单侧性,且多位于视乳头旁区域。高达三分之一的病例可能会发生脉络膜新生血管。脉络膜骨瘤必须与其他眼内肿瘤以及营养不良性和转移性钙化相鉴别。超声检查和计算机断层扫描可通过显示脉络膜水平的钙化斑块来辅助诊断。荧光素血管造影和吲哚菁绿血管造影可显示脉络膜新生血管,后者可能适合激光光凝治疗。

相似文献

1
Choroidal osteoma.脉络膜骨瘤
Int Ophthalmol Clin. 1997 Fall;37(4):171-82. doi: 10.1097/00004397-199703740-00015.
2
Choroidal osteoma: observations from a community setting.脉络膜骨瘤:来自社区环境的观察
Ophthalmology. 2003 Jul;110(7):1327-34. doi: 10.1016/S0161-6420(03)00458-5.
3
A case of choroidal osteoma with subsequent laser induced decalcification.一例脉络膜骨瘤继发激光诱导脱钙的病例。
Int Ophthalmol. 2001;24(1):41-3. doi: 10.1023/a:1014470730194.
4
[Choroidal osteoma--diagnosis and ophthalmic management ].[脉络膜骨瘤——诊断与眼科治疗]
Klin Oczna. 2002;104(3-4):271-5.
5
Midperipheral mottling pigmentation with familial choroidal osteoma.伴有家族性脉络膜骨瘤的中周边部斑驳状色素沉着。
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6
Indocyanine green video-angiographic findings in choroidal osteoma.脉络膜骨瘤的吲哚菁绿视频血管造影结果
Eur J Ophthalmol. 1994 Oct-Dec;4(4):191-8. doi: 10.1177/112067219400400401.
7
[Worsening of vision with apparent changes of the posterior pole].
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8
Classification of choroidal neovascularization by digital indocyanine green videoangiography.通过数字吲哚菁绿视频血管造影对脉络膜新生血管进行分类。
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9
Choroidal osteoma in a preterm infant.早产儿脉络膜骨瘤。
Indian J Ophthalmol. 2018 Apr;66(4):583-585. doi: 10.4103/ijo.IJO_914_17.
10
Bilateral choroidal osteoma with optic atrophy.双侧脉络膜骨瘤伴视神经萎缩。
J AAPOS. 2010 Oct;14(5):438-40. doi: 10.1016/j.jaapos.2010.06.015.

引用本文的文献

1
Spontaneous Resolution of Subretinal Detachment in Choroidal Osteoma Unresponsive to Antivascular Endothelial Growth Factor Agent and Multimodal Imaging: A Case Report.脉络膜骨瘤中视网膜下脱离的自发消退:对抗血管内皮生长因子药物无反应及多模态成像的病例报告
Korean J Ophthalmol. 2023 Feb;37(1):82-84. doi: 10.3341/kjo.2022.0113. Epub 2022 Oct 25.
2
Secondary choroidal neovascularization due to choroidal osteoma after 9 years follow-up.随访 9 年后因脉络膜骨瘤导致的脉络膜新生血管。
BMC Ophthalmol. 2021 May 31;21(1):242. doi: 10.1186/s12886-021-02004-3.
3
Bilateral pale posterior pole sans pain: A "hard" sell.
双侧后极部苍白且无疼痛:一项“难以推销”的情况。
Indian J Ophthalmol. 2019 May;67(5):582. doi: 10.4103/ijo.IJO_1949_18.
4
Diagnosis and Monitoring of Choroidal Osteoma through Multimodal Imaging.通过多模态成像诊断和监测脉络膜骨瘤
Case Rep Med. 2014;2014:393804. doi: 10.1155/2014/393804. Epub 2014 Sep 8.
5
Review of choroidal osteomas.脉络膜骨瘤综述。
Middle East Afr J Ophthalmol. 2014 Jul-Sep;21(3):244-50. doi: 10.4103/0974-9233.134686.
6
Choroidal osteoma with CNVM - Successful treatment with intravitreal Bevacizumab.伴有脉络膜新生血管的脉络膜骨瘤——玻璃体内注射贝伐单抗治疗成功
Saudi J Ophthalmol. 2011 Apr;25(2):199-202. doi: 10.1016/j.sjopt.2010.11.005. Epub 2010 Nov 13.
7
Combination therapy of low-fluence photodynamic therapy and intravitreal ranibizumab for choroidal neovascular membrane in choroidal osteoma.低强度光动力疗法联合玻璃体内雷珠单抗治疗骨瘤性脉络膜新生血管膜。
Indian J Ophthalmol. 2011 Sep-Oct;59(5):394-6. doi: 10.4103/0301-4738.83622.
8
Choroidal osteoma with choroidal neovascular membrane: Successful treatment with intravitreal bevacizumab.伴有脉络膜新生血管膜的脉络膜骨瘤:玻璃体内注射贝伐单抗治疗成功
Clin Ophthalmol. 2010 Oct 5;4:1081-4. doi: 10.2147/OPTH.S13730.
9
Choroidal osteoma in association with Stargardt's dystrophy.脉络膜骨瘤合并斯塔加特病。
Br J Ophthalmol. 2007 Jul;91(7):978-9. doi: 10.1136/bjo.2006.098186.
10
[Unilateral visual deterioration due to macular tumour of unclear origin. 32-year old female patient with sudden low vision in the right eye].
Ophthalmologe. 2003 Nov;100(11):984-7. doi: 10.1007/s00347-002-0778-7.