Kadrmas E F, Weiter J J
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston 02114, USA.
Int Ophthalmol Clin. 1997 Fall;37(4):171-82. doi: 10.1097/00004397-199703740-00015.
The choroidal osteoma is a benign, ossifying tumor of the choroid that typically is found in young, healthy women in the second or third decade of life. Its pathogenesis is unknown. This tumor is clinically unilateral in 75% of cases and tends to be located in the juxtapapillary region. Choroidal neovascularization may occur in up to one-third of cases. The choroidal osteoma must be differentiated from other intraocular tumors as well as cases of dystrophic and metastatic calcification. Ultrasonography and computed tomography may help in the diagnosis by demonstrating a calcified plaque at the level of the choroid. Fluorescein angiography and ICG videoangiography may demonstrate choroidal neovascularization, which may be amenable to treatment by laser photocoagulation.
脉络膜骨瘤是一种脉络膜的良性骨化性肿瘤,多见于20至30岁的年轻健康女性。其发病机制尚不清楚。该肿瘤75%的病例临床上为单侧性,且多位于视乳头旁区域。高达三分之一的病例可能会发生脉络膜新生血管。脉络膜骨瘤必须与其他眼内肿瘤以及营养不良性和转移性钙化相鉴别。超声检查和计算机断层扫描可通过显示脉络膜水平的钙化斑块来辅助诊断。荧光素血管造影和吲哚菁绿血管造影可显示脉络膜新生血管,后者可能适合激光光凝治疗。