Auditory Group, Institute of Neuroscience, Newcastle University Newcastle Upon Tyne, UK.
Front Neurosci. 2014 Jul 21;8:198. doi: 10.3389/fnins.2014.00198. eCollection 2014.
Recent neuroimaging studies in primates aim to define the functional properties of auditory cortical areas, especially areas beyond A1, in order to further our understanding of the auditory cortical organization. Precise mapping of functional magnetic resonance imaging (fMRI) results and interpretation of their localizations among all the small auditory subfields remains challenging. To facilitate this mapping, we combined here information from cortical folding, micro-anatomy, surface-based atlas and tonotopic mapping. We used for the first time, phase-encoded fMRI design for mapping the monkey tonotopic organization. From posterior to anterior, we found a high-low-high progression of frequency preference on the superior temporal plane. We show a faithful representation of the fMRI results on a locally flattened surface of the superior temporal plane. In a tentative scheme to delineate core versus belt regions which share similar tonotopic organizations we used the ratio of T1-weighted and T2-weighted MR images as a measure of cortical myelination. Our results, presented along a co-registered surface-based atlas, can be interpreted in terms of a current model of the monkey auditory cortex.
最近的灵长类动物神经影像学研究旨在定义听觉皮层区域的功能特性，特别是 A1 以外的区域，以进一步了解听觉皮层组织。精确映射功能磁共振成像 (fMRI) 结果并解释它们在所有小听觉子场中的定位仍然具有挑战性。为了促进这种映射，我们在这里结合了皮质折叠、微观解剖、基于表面的图谱和音调映射的信息。我们首次使用相位编码 fMRI 设计来绘制猴子的音调组织图。从前到后，我们在颞上平面上发现了频率偏好的高低高进展。我们在颞上平面的局部扁平表面上展示了 fMRI 结果的忠实表示。在一个用于描绘具有相似音调组织的核心与带区的试探性方案中，我们使用 T1 加权和 T2 加权 MR 图像的比值作为皮质髓鞘化的度量。我们沿着配准的基于表面的图谱呈现的结果可以根据当前的猴子听觉皮层模型来解释。
