Pediatric Gastroenterology and Nutrition Unit, Meyer Children's Hospital of Haifa, Rambam Medical Center , Haifa , Israel ; Department of Pediatrics, Carmel Medical Center, Faculty of Medicine, Technion - Israel Institute of Technology , Haifa , Israel.
Pediatric Gastroenterology and Nutrition Unit, Meyer Children's Hospital of Haifa, Rambam Medical Center , Haifa , Israel.
Front Pediatr. 2014 Jul 21;2:73. doi: 10.3389/fped.2014.00073. eCollection 2014.
There is growing evidence that nutrition is part of the environmental factors affecting the incidence of various diseases. The effect starts in the prenatal life and affects fetal growth and continues in early life and throughout childhood. The effect has been shown on various disease states such as allergic diseases, hyperlipidemia and cardiovascular diseases, obesity, type II diabetes and metabolic syndrome, and immunologic diseases such as celiac disease and type 1 diabetes mellitus. It seems that the recommendations of exclusive breastfeeding until the age of 4 months and subsequently exposure to various solid foods has beneficial effect in terms of allergic, immunologic, and cardiovascular diseases prevention. Will these recommendations change the natural course of these diseases is unknown yet, but there is accumulating evidence that indeed this is the case. In this review, we review the evidence of early nutritional intervention and future disease prevention.
越来越多的证据表明,营养是影响各种疾病发病率的环境因素之一。这种影响始于胎儿期,影响胎儿生长,并在生命早期和整个儿童期持续存在。这种影响已在各种疾病状态中得到证实,如过敏疾病、高脂血症和心血管疾病、肥胖、2 型糖尿病和代谢综合征以及免疫疾病,如乳糜泻和 1 型糖尿病。看来,建议纯母乳喂养至 4 个月大,然后接触各种固体食物,对预防过敏、免疫和心血管疾病有有益的效果。这些建议是否会改变这些疾病的自然病程尚不清楚,但越来越多的证据表明情况确实如此。在这篇综述中,我们回顾了早期营养干预和未来疾病预防的证据。