Paick Jae-Seung, Um Jin Mo, Kim Soo Woong, Ku Ja Hyeon
Department of Urology, Seoul National University Hospital, Jongno Ku, Seoul, Korea.
J Sex Med. 2007 Nov;4(6):1701-7. doi: 10.1111/j.1743-6109.2007.00574.x. Epub 2007 Aug 2.
Erectile function after high-power potassium-titanyl-phosphate (KTP) photoselective laser vaporization of the prostate has not been investigated systemically.
The aim of this study was to evaluate the impact of high-power KTP photoselective laser vaporization of the prostate on erectile function in men with lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia.
A total of 45 patients with mean age of 68.3 years (range 56-86) were included in the primary analysis. At baseline and at 6-month postoperative visit, the International Index of Erectile Function (IIEF), International Prostate Symptom Score (IPSS), maximum flow rate (Qmax), and post-void residual urine (PVR) volume were evaluated.
The primary efficacy outcome was changes in the "erectile function" domain and other sexual functions. The secondary outcome was changes in LUTS.
Six months after surgery, data of the IPSS, Qmax, and PVR volume improved (P < 0.05). All IIEF domains also improved 6 months after surgery (P < 0.05). "Erectile function" domain increased from a baseline of 11.3 +/- 1.8 to 14.7 +/- 1.7 (P = 0.015). Overall, the IIEF total sum increased from a baseline mean of 27.4 +/- 3.8 to 34.9 +/- 3.7 after KTP photoselective vaporization of the prostate (P = 0.010).
The present results suggest that 6 months after high-power KTP laser vaporization, sexual functions including erectile function improved. However, as with any new technique, a longer follow-up and a larger cohort are needed further to validate these findings.
高功率磷酸钛氧钾(KTP)前列腺光选择性汽化术后的勃起功能尚未得到系统性研究。
本研究旨在评估高功率KTP前列腺光选择性汽化术对下尿路症状(LUTS)/良性前列腺增生男性勃起功能的影响。
共有45例平均年龄68.3岁(范围56 - 86岁)的患者纳入初步分析。在基线期和术后6个月随访时,评估国际勃起功能指数(IIEF)、国际前列腺症状评分(IPSS)、最大尿流率(Qmax)和残余尿量(PVR)。
主要疗效指标为“勃起功能”领域及其他性功能的变化。次要指标为LUTS的变化。
术后6个月,IPSS、Qmax和PVR数据有所改善(P < 0.05)。术后6个月所有IIEF领域也有所改善(P < 0.05)。“勃起功能”领域从基线的11.3±1.8增加到14.7±1.7(P = 0.015)。总体而言,KTP前列腺光选择性汽化术后IIEF总分从基线平均值27.4±3.8增加到34.9±3.7(P = 0.010)。
目前结果表明,高功率KTP激光汽化术后6个月,包括勃起功能在内的性功能有所改善。然而,与任何新技术一样,需要更长时间的随访和更大规模的队列进一步验证这些发现。