伯苄基卤化物和仲苄基卤化物与芳基硼酸酯的铜催化铃木-宫浦反应。
Cu-catalyzed Suzuki-Miyaura reactions of primary and secondary benzyl halides with arylboronates.
作者信息
Sun Yan-Yan, Yi Jun, Lu Xi, Zhang Zhen-Qi, Xiao Bin, Fu Yao
机构信息
Anhui Province Key Laboratory of Biomass Clean Energy Department of Chemistry, University of Science and Technology of China, Hefei 230026, P. R. China.
出版信息
Chem Commun (Camb). 2014 Sep 28;50(75):11060-2. doi: 10.1039/c4cc05376a. Epub 2014 Aug 7.
A copper-catalyzed Suzuki-Miyaura coupling of benzyl halides with arylboronates is described. Varieties of primary benzyl halides as well as more challenging secondary benzyl halides with β hydrogens or steric hindrance could be successfully converted into the corresponding products. Thus it provides access to diarylmethanes, diarylethanes and triarylmethanes.
本文描述了一种铜催化的苄基卤化物与芳基硼酸酯的铃木-宫浦偶联反应。各种伯苄基卤化物以及更具挑战性的带有β氢或空间位阻的仲苄基卤化物都能成功转化为相应的产物。因此，该反应为合成二芳基甲烷、二芳基乙烷和三芳基甲烷提供了途径。
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