Berezin M, Ohry A, Shemesh Y, Zeilig G, Brooks M E
Institute of Endocrinology, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
Gynecol Endocrinol. 1989 Jun;3(2):159-63. doi: 10.3109/09513598909152463.
Six women with a traumatic spinal cord injury (SCI) developed hyperprolactinemia, amenorrhea and galactorrhea. Five of them had thoracic level lesions and 1 had a lumbosacral lesion. Two were postpartum and 1 was pregnant at the time of injury. Transient diabetes insipidus developed in 1 patient. Temporary administration of bromocriptine decreased prolactin levels, caused cessation of lactation and restored ovulatory cycles. The syndrome disappeared spontaneously in all 6 patients. Pituitary stalk concussion resulting from the trauma might cause this phenomenon, with the level of the cord injury playing a role. Being pregnant or early postpartum can predispose women to develop this syndrome.
