Cruaud P, Berlie C, Torgal Garcia J, Papa F, David H L
Unité de la Tuberculose et des Mycobactéries, Institut Pasteur, Paris, France.
Zentralbl Bakteriol. 1989 Oct;271(4):481-5. doi: 10.1016/s0934-8840(89)80108-2.
IgG and IgM antibodies immunoreacting with sulfolipids from Mycobacterium tuberculosis were detected in sera from tuberculosis patients. The method used was an enzyme linked immunoassay (ELISA) and the antigens were a 2, 3, 6, 6' tetraacyl trehalose-2'-sulfate (sulfolipid I, SL I) and a 2, 3 diacyl trehalose-2'-sulfate (sulfolipid IV, SL IV). The SL IV antigen was satisfactory for IgG assays. The sensitivity and the specificity of the test were, respectively, 59 and 100%; the predictive values of a positive and negative test were, respectively, 100 and 76%.
在肺结核患者的血清中检测到了与结核分枝杆菌硫脂发生免疫反应的IgG和IgM抗体。所采用的方法是酶联免疫吸附测定法（ELISA），抗原为2,3,6,6'-四酰海藻糖-2'-硫酸盐（硫脂I，SL I）和2,3-二酰海藻糖-2'-硫酸盐（硫脂IV，SL IV）。SL IV抗原用于IgG检测效果良好。该检测的灵敏度和特异性分别为59%和100%；阳性检测和阴性检测的预测值分别为100%和76%。
