Randall J, Smyth E, McCarthy K, Dixon A R
University Hospitals Bristol, Bristol, UK.
Colorectal Dis. 2014 Nov;16(11):914-9. doi: 10.1111/codi.12741.
The study assessed the efficacy of laparoscopic ventral mesh rectopexy (LVMR) for full thickness external rectal prolapse (ERP), including recurrent prolapse.
A prospective database identified all patients undergoing LVMR for ERP over the 16-year period to December 2013. Clinical outcome, Cleveland Clinic Incontinence Score (CCIS), quality of life (QOL) and patient-reported outcome were evaluated.
In total, 190 LVMRs (87% women) were performed during the study period, with a median active follow-up of 29 (1-196) months; 120 had a follow-up > 5 years and 16 > 10 years. The median time from surgery was 73 (1-196) months. The 60-day mortality, recurrence and mesh-related complication rates were 1%, 3% and 3.7%. The mean improvement in CCIS was 8 (P < 0.0001). Sixty-two patients returned a complete sequence of QOL scores (Birmingham Bowel and Urinary Symptoms Questionnaire 22), which had improved by 46% at year 1 and were sustained at a median of 4 years (P < 0.001). Mean patient-reported outcome measures for satisfaction at final review in 119 responders was 9.1/10. Thirty-nine patients underwent LVMR for recurrent ERP following perineal repair. Of these, full thickness recurrence occurred in one and there were no mesh complications. The same sustained improvement in QOL was observed.
LVMR for ERP is associated with low morbidity and recurrence and a long-term improvement in function and QOL. LVMR achieves the same benefits after a failed perineal procedure.
本研究评估腹腔镜腹侧补片直肠固定术(LVMR)治疗全层直肠外脱垂(ERP)的疗效,包括复发性脱垂。
通过前瞻性数据库确定了在截至2013年12月的16年期间所有接受LVMR治疗ERP的患者。评估了临床结局、克利夫兰诊所失禁评分(CCIS)、生活质量(QOL)和患者报告的结局。
在研究期间共进行了190例LVMR手术(87%为女性),中位有效随访时间为29(1 - 196)个月;120例随访时间>5年,16例随访时间>10年。手术的中位时间为73(1 - 196)个月。60天死亡率、复发率和补片相关并发症发生率分别为1%、3%和3.7%。CCIS的平均改善值为8(P < 0.0001)。62例患者返回了完整的QOL评分序列(伯明翰肠道和泌尿症状问卷22),在第1年改善了46%,并在中位4年时保持稳定(P < 0.001)。119例应答者在最终复查时患者报告的满意度平均评分为9.1/10。39例患者在会阴修复后因复发性ERP接受了LVMR。其中,1例发生全层复发,无补片并发症。观察到QOL有同样持续的改善。
LVMR治疗ERP的发病率和复发率低,功能和QOL有长期改善。在会阴手术失败后,LVMR也能取得同样的效果。