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胃肠外给予脂肪会改变免疫能力吗?

[Does parenteral fat administration modify immunocompetence?].

作者信息

Thul P, Müller J M, Keller H W

机构信息

Chirurgische Universitätsklinik Köln-Lindenthal.

出版信息

Infusionstherapie. 1989 Oct;16(5):237-40.

PMID:2511148
Abstract

Evidence from studies in carcinoma patients who received intravenous glucose or glucose-lipid solutions preoperatively indicates that fibrinogen, alpha-II-macroglobulin, and coeruloplasmin serum levels remain unchanged. On the other hand, parenteral administration of lipids or glucose induces an increase of IgM, IgG, IgA and complement C3 serum concentrations. Cutaneous allergy testing shows no significant difference whether only glucose was used or half of the calories were replaced by 2.4 g lipids/kg BW x day.

摘要

对术前接受静脉输注葡萄糖或葡萄糖-脂质溶液的癌症患者的研究证据表明,纤维蛋白原、α-II-巨球蛋白和铜蓝蛋白的血清水平保持不变。另一方面,胃肠外给予脂质或葡萄糖会导致IgM、IgG、IgA和补体C3血清浓度升高。皮肤过敏试验显示,无论仅使用葡萄糖还是一半热量由每天每千克体重2.4克脂质替代,均无显著差异。

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