Jamil S
J Pak Med Assoc. 1989 Sep;39(9):239-40.
During a meningococcal outbreak, 221 patients were studied. A skin rash was present in 78 (35.3%) patients. Twenty one (11.3%) patients had a frankly purpuric rash, involving mainly the extremities and the remaining had a generalised macular or petechial lesions. Extensive purpuric lesions, involving mainly the extremities were associated with disseminated intravascular coagulation (DIC), shock and a fatal outcome. This peripherally distributed rash may be used as a clinical substitute for the laboratory tests that confirm DIC.
在一次脑膜炎球菌爆发期间，对221名患者进行了研究。78名（35.3%）患者出现皮疹。21名（11.3%）患者有明显的紫癜疹，主要累及四肢，其余患者有全身性斑疹或瘀点性损害。主要累及四肢的广泛紫癜性损害与弥散性血管内凝血（DIC）、休克及致命结局相关。这种外周分布的皮疹可作为确诊DIC的实验室检查的临床替代指标。
