Ozyigit Gokhan, Gultekin Melis
Gokhan Ozyigit, Melis Gultekin, Department of Radiation Oncology, Cancer Institute, Hacettepe University Faculty of Medicine, 06100 Ankara,Turkey.
World J Clin Oncol. 2014 Aug 10;5(3):425-39. doi: 10.5306/wjco.v5.i3.425.
Breast cancer is the most common type of malignancy in females. Advances in systemic therapies and radiotherapy (RT) provided long survival rates in breast cancer patients. RT has a major role in the management of breast cancer. During the past 15 years several developments took place in the field of imaging and irradiation techniques, intensity modulated RT, hypofractionation and partial-breast irradiation. Currently, improvements in the RT technology allow us a subsequent decrease in the treatment-related complications such as fibrosis and long-term cardiac toxicity while improving the loco-regional control rates and cosmetic results. Thus, it is crucial that modern radiotherapy techniques should be carried out with maximum care and efficiency. Several randomized trials provided evidence for the feasibility of modern radiotherapy techniques in the management of breast cancer. However, the role of modern radiotherapy techniques in the management of breast cancer will continue to be defined by the mature results of randomized trials. Current review will provide an up-to-date evidence based data on the role of modern radiotherapy techniques in the management of breast cancer.
乳腺癌是女性最常见的恶性肿瘤类型。全身治疗和放射治疗(RT)的进展提高了乳腺癌患者的长期生存率。RT在乳腺癌的治疗中起着重要作用。在过去15年里,成像和照射技术、调强放疗、大分割放疗和部分乳腺照射领域取得了多项进展。目前,RT技术的改进使我们能够在降低诸如纤维化和长期心脏毒性等与治疗相关并发症的同时,提高局部区域控制率和美容效果。因此,至关重要的是,现代放疗技术应极其谨慎且高效地实施。多项随机试验为现代放疗技术在乳腺癌治疗中的可行性提供了证据。然而,现代放疗技术在乳腺癌治疗中的作用仍将由随机试验的成熟结果来确定。本综述将提供关于现代放疗技术在乳腺癌治疗中作用的最新循证数据。