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从雷公藤(Tripterygium wilfordii Hook.)中分离出的一种真菌内生菌——枝孢霉属(Rhinocladiella sp.)lgt-3产生的两种新环二肽

Two new cyclic dipeptides from Rhinocladiella sp. lgt-3, a fungal endophyte isolated from Tripterygium wilfordii Hook.

作者信息

Zhang Dong-Bo, Yang Zhong-Duo, Xue Peng-Hui, Zhi Kang-Kang, Shi Yin, Wang Ming-Gang

机构信息

a School of Life Science and Engineering, Lanzhou University of Technology , Lanzhou , 730050 , P.R. China.

出版信息

Nat Prod Res. 2014;28(20):1760-4. doi: 10.1080/14786419.2014.945176. Epub 2014 Aug 12.

Abstract

Two new cyclic dipeptides, rhinocladin A (1) and rhinocladin B (2), were isolated from a fungal endophyte (Rhinocladiella sp. lgt-3) of Tripterygium wilfordii Hook. Their structures were elucidated by 1D and 2D NMR spectra. The monoamine oxidase inhibitory activity of 1 and 2 was also evaluated.

摘要

从雷公藤(Tripterygium wilfordii Hook.)的一种真菌内生菌(枝孢霉属菌株lgt-3)中分离出两种新的环二肽,即枝孢菌素A(1)和枝孢菌素B(2)。通过一维和二维核磁共振光谱对它们的结构进行了阐明。还评估了1和2的单胺氧化酶抑制活性。

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